The Zen of Technology & Scientific Discovery! (& Robots)

Collapse
X
 
  • Time
  • Show
Clear All
new posts

  • Jundo
    replied
    Let's hope so ...

    Easily synthesized chemical filter could stop the greenhouse gas from reaching the atmosphere.

    How can carbon dioxide, a greenhouse gas, be removed from the exhaust of fossil fuel power plants before it ever enters the atmosphere? New research findings suggest that a promising answer lies in a simple, economical, and potentially reusable material that was analyzed at the National Institute of Standards and Technology (NIST). Scientists there from multiple institutions have determined why this material works as well as it does.

    Aluminum formate was the team’s object of study. It is one of a class of substances called metal-organic frameworks (MOFs). As a group, MOFs have exhibited tremendous potential for filtering and separating organic materials — often the various hydrocarbons in fossil fuels — from one another. Some MOFs have shown promise at refining natural gas or separating the octane components of gasoline; others might contribute to reducing the cost of plastics manufacturing or cheaply converting one substance to another. Their capacity to perform such separations comes from their inherently porous nature.

    Aluminum formate, which the scientists refer to as ALF, has a talent for separating carbon dioxide (CO2) from the other gases that commonly fly out of the smokestacks of coal-fired power plants. According to NIST’s Hayden Evans, it also lacks the shortcomings that other proposed carbon filtration materials have. Evans is one of the lead authors of the team’s research paper, which was published on November 2 in the peer-reviewed journal Science Advances.

    “What makes this work exciting is that ALF performs really well relative to other high-performing CO2 adsorbents, but it rivals designer compounds in its simplicity, overall stability and ease of preparation,” said Evans, a chemist at the NIST Center for Neutron Research (NCNR). “It is made of two substances found easily and abundantly, so creating enough ALF to use widely should be possible at very low cost.”
    https://scitechdaily.com/nist-breakt...t-smokestacks/
    That's our scientists, using their brains ... or parts of them anyway ...

    The Brain Isn’t Symmetrical – Researchers Reveal New Insight About the Brain

    At first glance, the human body seems to be symmetrical: two arms, two legs, two eyes, two ears, and even the nose and mouth appear to be mirrored on an imaginary axis that divides most people’s faces. Finally, the brain is split into two nearly equal-sized halves, and the furrows and bulges follow a similar pattern. The initial impression, however, is misleading since there are small, functionally relevant differences between the left and right sides of the different brain regions.

    The two hemispheres have distinct functional specializations. For instance, most individuals process language mostly in their left hemisphere whereas spatial attention is primarily processed in their right hemisphere. Work can thus be distributed more effectively to both sides, and the overall range of tasks is expanded.

    However, this so-called lateralization, or the tendency for brain regions to process certain functions more in the left or right hemisphere, differs between people. And not only in the minority whose brains are mirror-inverted in comparison to the majority. Even people with classically arranged brains have varying degrees of asymmetry. Previous research has indicated that this, in turn, may have an effect on the functions themselves.

    For instance, dyslexia is characterized by a lack of left asymmetry in certain language areas. Inadequate brain lateralization may also contribute to conditions such as schizophrenia, autism spectrum disorders, and children’s hyperactivity.

    Until now, however, it hasn’t been clear how much brain asymmetry variance, across individuals, is heritable and how much is due to different demands. Furthermore, are similar features of brain asymmetry also present in monkeys?

    Scientists at the Max Planck Institute for Human Cognitive and Brain Sciences (MPI CBS) and Forschungszentrum Juelich (FZJ) have now investigated the asymmetry of functional gradients, describing axes of smooth variations of brain function across the cortex. They found that there are subtle variations in the functional organization of brain regions on the left and right sides of the brain. On the left side, regions involved in language processing are most distant from those implicated in vision and sensation.

    Whereas on the right side the so-called frontoparietal network, responsible for attention and working memory, for example, is most distant from those sensory regions. The researchers also found that individual differences in these functional arrangements were heritable, meaning that they are partly influenced by genetic factors. At the same time, a large portion of this asymmetry in human brains could not be accounted for by genetic factors. This means some asymmetry is influenced, at least in part, by the person’s experience.

    https://scitechdaily.com/the-brain-i...out-the-brain/
    I grew up with a kind of dyslexia, plus have some memory issues related to names of people and some other oddities, so this is very interesting. I actually do better reading Japanese/Chinese characters than English letters! I can blame my lopsided brain!

    Gassho, J

    stlah

    Leave a comment:


  • Jundo
    replied
    It is all in the bones ...

    Scientists have finally solved a centuries-old riddle in the evolution of life on earth, revealing what the first animals to make skeletons looked like. This discovery was possible due to an exceptionally well-preserved collection of fossils discovered in eastern Yunnan Province, China. The results of the research were published on November 2 in the scientific journal Proceedings of the Royal Society B.

    During an event called the Cambrian Explosion around 550-520 million years ago, the first animals to build hard and robust skeletons appear suddenly in the fossil record in a geological blink of an eye. Many of these early fossils are simple hollow tubes ranging from a few millimeters to many centimeters in length. However, what sort of animals made these skeletons was almost completely unknown, because they lack preservation of the soft parts needed to identify them as belonging to major groups of animals that are still alive today.

    Four specimens of Gangtoucunia aspera with soft tissues still intact, including the gut and mouthparts, are included in the new collection of 514 million-year-old fossils. ...

    According to the researchers, Gangtoucunia would have looked similar to modern scyphozoan jellyfish polyps, with a hard tubular structure anchored to the underlying substrate. The tentacle mouth would have extended outside the tube, but could have been retracted inside the tube to avoid predators. Unlike living jellyfish polyps, however, the tube of Gangtoucunia was made of calcium phosphate, a hard mineral that makes up our own teeth and bones. Use of this material to build skeletons has become more rare among animals over time.


    Artist’s reconstruction of Gangtoucunia aspera as it would have appeared in life on the Cambrian seafloor, circa 514 million years ago. The individual in the foreground has part of the skeleton removed to show the soft polyp inside the skeleton.

    Gassho, J

    stlah

    Leave a comment:


  • Jundo
    replied
    This is just so beautiful, a dance of partners ...

    Two of the galaxies in the galactic triplet Arp 248 — also known as Wild’s Triplet — are seen in this image from the NASA/ESA Hubble Space Telescope. Arp 248 is located approximately 200 million light-years from Earth in the constellation Virgo. The two large spiral galaxies visible in this image — which flank a smaller, unrelated background spiral galaxy — appear to be connected by a luminous bridge. Known as a tidal tail, this elongated stream of stars and interstellar dust was formed by the mutual gravitational attraction of the two foreground galaxies.

    https://scitechdaily.com/hubble-spac...pace-oddities/

    Gassho, J

    stlah

    Leave a comment:


  • Jundo
    replied
    Three for the price of one ...

    The James Webb Space Telescope has provided astronomers with a glimpse of the early universe in a new image shared on Wednesday. ... The telescope captured an image of a galaxy cluster called MACS0647, as well as the distant galaxy MACS0647-JD [that is within that cluster]. The cluster appears as a dazzling grouping of galaxies that seem to shine like precious gems against the dark backdrop of space.

    The distant galaxy is visible because of a certain type of observational phenomenon due to the cluster. This phenomenon, called gravitational lensing, occurs when foreground galaxies act as a magnifying glass for the more distant objects behind them. Small boxes were used to pinpoint the galaxy MACS0647-JD, and more detailed images of the galaxy are aligned along the right side of the image. The cluster essentially triple lensed the galaxy, magnifying it and causing it to appear in three separate places within the image. Each box on the right showcases different details of the galaxy.

    “With Hubble, it was just this pale, red dot. We could tell it was really small, just a tiny galaxy in the first 400 million years of the universe,” said Coe, a Space Telescope Science Institute astronomer for the European Space Agency ... “Now we look with Webb, and we’re able to resolve TWO objects! We’re actively discussing whether these are two galaxies or two clumps of stars within a galaxy. We don’t know, but these are the questions that Webb is designed to help us answer.” The two objects differ in color, with one being more blue while the other is more red. The colors indicate different gases. While the blue object indicates the formation of young stars, the red object is dusty and older. Astronomers think that the two objects in the galaxy image may suggest ... a merger between two galaxies.

    https://us.cnn.com/2022/10/26/world/...scn/index.html

    and ... our ancient fish ancestors ... filling in the gaps in the history of our jaws and of our teeth ...

    New Findings Rewrite the Evolutionary Story of “Fish to Human”

    Researchers from the Chinese Academy of Sciences‘ Institute of Vertebrate Paleontology and Paleoanthropology (IVPP) have recently found two fossil repositories in the early Silurian strata of southwest Guizhou and Chongqing that are rewriting the “from fish to human” evolutionary story. Four different papers describing their findings were recently published in the journal Nature.

    Humans are one of the 99.8% of species of extant vertebrates that are gnathostomes, or jawed vertebrates. The basic body plan and several key organs of humans can be traced back to the origin of gnathostomes. One of the most significant developments in the evolution of vertebrates is the emergence of jaws.

    However, how this innovation occurred remains a mystery, owing to the fact that fossils of early jawed vertebrates were not discovered in large numbers until the beginning of the Devonian (419 million years ago), despite molecular data indicating that the origin of jawed vertebrates should have occurred earlier than 450 million years ago. As a result, there is a significant gap in the fossil record of early jawed vertebrates, lasting at least 30 million years from the Late Ordovician to the Silurian.

    The latest findings of Zhu Min’s team from IVPP are unearthed from two new fossil depositories, shedding light on the rise of jawed vertebrates: These jawed fishes were already thriving in the waters of the South China block, at least 440 million years ago, and by late Silurian, more diverse and larger jawed fishes had evolved and began to spread around the world ... Discoveries of fish fossils from the two depositories help to trace many human body structures back to ancient fishes, some 440 million years ago and fill some key gaps in the evolution of “from fish to human,” and provide further iron evidence to the evolutionary path.

    https://scitechdaily.com/new-finding...fish-to-human/
    The below picture summarizes the findings. Think about this, the next time you eat lunch or visit the dentist!


    Bite into that!

    Below, see your ancestors swim ... clear to the bottom ...


    Gassho, J

    stlah
    Last edited by Jundo; 10-27-2022, 01:30 AM.

    Leave a comment:


  • Jundo
    replied
    Finding a pin in a haystack ... in a mountain of haystacks ...

    Scientists Successfully Track Down a “Mystery Gene” ... The gene matures the skeleton of the cell.

    “I’m a professional pin-in-a-haystack seeker,” geneticist Thijn Brummelkamp responded when asked why he succeeds at finding proteins and genes that others have missed, despite the fact that some have remained elusive for as long as forty years. His research group at the Netherlands Cancer Institute has once again identified one of these “mystery genes” – the gene that guarantees the final form of the protein actin, a key component of our cell skeleton – is produced. These findings were recently published in the journal Science.

    Actin is one of the most common molecules in a cell and a key component of the cell skeleton, which is why cell biologists are particularly interested in it. In our lifetime, we produce more than 100 kilograms of actin. It is present in large amounts in all cell types and has a variety of functions, including giving cells structure and making them firmer, playing a key role in cell division, propelling cells forward, and giving our muscles strength. People who have defective actin proteins often have muscle disease. Much is known about actin’s function, but how is the final version of this vital protein produced and which gene is responsible? “We didn’t know,” says Brummelkamp ...

    ... Before a protein is completely “finished” – or mature, as the researchers describe it in Science – and can fully perform its function in the cell, it usually has to be stripped of a specific amino acid first. This amino acid is then cut from a protein by a pair of molecular scissors. This is also what occurs with actin. It was known on which side of the actin the relevant amino acid is cut off. However, no one managed to find the enzyme that acts as scissors in this process. ...

    ... Then came the “eureka”-moment: Haahr had traced down the molecular scissors that cut the essential amino acid from actin. Those scissors turned out to be controlled by a gene with a previously unknown function ...

    ... ACTMAP is not the first mystery gene discovered by Brummelkamp that plays a role in our cell skeleton function. Using the same method, his group has been able to detect three unknown molecular scissors over recent years that cut an amino acid from tubulin, the other main component of the cell skeleton. These scissors allow tubulin to perform its dynamic functions properly inside the cell.

    Leave a comment:


  • Jundo
    replied
    Never forget how special is the planet on which we live ... and it just got a little more special ...

    The hunt for habitable planets may have just gotten far more narrow, new study finds


    The hunt for planets that could harbor life may have just narrowed dramatically.

    Scientists had long hoped and theorized that the most common type of star in our universe — called an M dwarf — could host nearby planets with atmospheres, potentially rich with carbon and perfect for the creation of life. But in a new study of a world orbiting an M dwarf 66 light-years from Earth, researchers found no indication such a planet could hold onto an atmosphere at all.

    Without a carbon-rich atmosphere, it’s unlikely a planet would be hospitable to living things. Carbon molecules are, after all, considered the building blocks of life. And the findings don’t bode well for other types of planets orbiting M dwarfs, said study coauthor Michelle Hill, a planetary scientist and a doctoral candidate at the University of California, Riverside.

    “The pressure from the star’s radiation is immense, enough to blow a planet’s atmosphere away,” Hill said in a post on the university’s website.

    M dwarf stars are known to be volatile, sputtering out solar flares and raining radiation on nearby celestial bodies. But for years, the hope had been that fairly large planets orbiting near M dwarfs could be in a Goldilocks environment, close enough to their small star to keep warm and large enough to cling onto its atmosphere.

    The nearby M dwarf, however, could be too intense to keep the atmosphere intact, according to the new study, which was published in The Astrophysical Journal Letters.

    A similar phenomenon happens in our solar system: Earth’s atmosphere also deteriorates because of outbursts from its nearby star, the sun. The difference is that Earth has enough volcanic activity and other gas-emitting activity to replace the atmospheric loss and make it barely detectable, according to the research.

    However, the M dwarf planet examined in the study, GJ 1252b, “could have 700 times more carbon than Earth has, and it still wouldn’t have an atmosphere. It would build up initially, but then taper off and erode away,” said study coauthor and UC Riverside astrophysicist Stephen Kane, in a news release.

    GJ 1252b orbits less than a million miles from its home star, called GJ_1252. The planet reaches sweltering daytime temperatures of up to 2,242 degrees Fahrenheit (1,228 degrees Celsius), the study found.
    However ...

    There are, however, still plenty of interesting places to hunt for habitable worlds. Apart from looking to planets farther away from M dwarfs that could be more likely to retain an atmosphere, there are still roughly 1,000 sunlike stars relatively near Earth that could have their own planets circling within habitable zones, according to the UC Riverside post about the study.

    https://us.cnn.com/2022/10/25/world/...scn/index.html
    ... and on the other hand ...

    A new study finds the chances of uncovering life on Mars are better than previously expected.

    Researchers simulated Mars’ harsh ionizing radiation conditions to see how long dried, frozen bacteria and fungi could survive.

    Previous studies found ‘Conan the Bacterium’ (Deinococcus radiodurans) could survive over a million years in Mars’ harsh ionizing radiation.

    A new study shatters that record, finding the hearty bacterium could survive 280 million years if buried.
    This means evidence of life could still be dormant and buried below Mars’ surface.

    ... Because the scientists proved that certain strains of bacteria can survive despite Mars’ harsh environment, this also means that future astronauts and space tourists could inadvertently contaminate Mars with their own hitchhiking bacteria.
    ... and ... possible Invaders from Mars! ...

    “We concluded that terrestrial contamination on Mars would essentially be permanent — over timeframes of thousands of years,” said Hoffman, a senior co-author of the study. “This could complicate scientific efforts to look for Martian life. Likewise, if microbes evolved on Mars, they could be capable of surviving until present day. That means returning Mars samples could contaminate Earth.”



    Gassho, J

    stlah
    Last edited by Jundo; 10-26-2022, 12:04 AM.

    Leave a comment:


  • Jundo
    replied
    But wait a second ...

    When the ARGHAP11B gene was knocked out in human brain organoids or the ARHGAP11B protein’s function was inhibited, the number of these brain stem cells was reduced to that of a chimpanzee.
    So, does that mean that, if we were to crispr ARGHAP11B into a chimpanzee brain, the result is this?


    Fiction becomes fact?

    Gassho, J

    stlah

    Leave a comment:


  • Jundo
    replied
    Scientists used their big brains to find this ...

    Scientists Uncover the Gene Responsible for Human’s Big Brain

    Great ape animal studies have long been prohibited in Europe due to ethical concerns. An alternative to using animals in studies is the use of so-called organoids, which are three-dimensional cell structures that can be generated in the lab and are just a few millimeters in size. These organoids can be created using pluripotent stem cells, which then subsequently develop into particular cell types like nerve cells. The study team was able to create both chimpanzee and human brain organoids by using this method.

    “These brain organoids allowed us to investigate a central question concerning ARHGAP11B,” says Wieland Huttner of the Max Planck Institute of Molecular Cell Biology and Genetics, one of the three lead authors of the study.

    “In a previous study, we were able to show that ARHGAP11B can enlarge a primate brain. However, it was previously unclear whether ARHGAP11B had a major or minor role in the evolutionary enlargement of the human neocortex,” says Wieland Huttner. ... “Our study shows that the gene in chimpanzee organoids causes an increase in relevant brain stem cells and an increase in those neurons that play a crucial role in the extraordinary mental abilities of humans,” said Michael Heide, the study’s lead author, who is head of the Junior Research Group Brain Development and Evolution at the German Primate Center and employee at the MPI-CBG.

    When the ARGHAP11B gene was knocked out in human brain organoids or the ARHGAP11B protein’s function was inhibited, the number of these brain stem cells was reduced to that of a chimpanzee.

    https://scitechdaily.com/scientists-...ans-big-brain/
    Gassho, J

    stlah

    Leave a comment:


  • Jundo
    replied
    A bit beyond my brain to fathom, quantum or otherwise, but fascinating nonetheless ...

    Shocking Experiment Indicates Our Brains Use Quantum Computation

    Scientists believe our brains could use quantum computation after taking a concept developed to prove the existence of quantum gravity and adapting it to explore the human brain and its workings. The discovery may shed light on consciousness, the workings of which remain scientifically difficult to understand and explain. Quantum brain processes could also explain why humans can still outperform supercomputers when it comes to unforeseen circumstances, decision-making, or learning something new.

    After adapting an idea developed to prove the existence of quantum gravity to explore the human brain and its workings, researchers from Trinity College Dublin think that human brains could use quantum computation. The brain functions measured in the experiment were also correlated to short-term memory performance and conscious awareness. This suggests that quantum processes are also part of cognitive and conscious brain functions.

    If the team’s results can be corroborated, which would likely require advanced multidisciplinary approaches, they would improve our general understanding of how the brain works. The insights could potentially reveal how the brain can be maintained or even healed. They may also help uncover innovative technologies and build even more advanced quantum computers.

    Dr. Christian Kerskens is the co-author of the research article that was published on October 7 in the Journal of Physics Communications. He is also lead physicist at the Trinity College Institute of Neuroscience (TCIN), He said:

    “We adapted an idea, developed for experiments to prove the existence of quantum gravity, whereby you take known quantum systems, which interact with an unknown system. If the known systems entangle, then the unknown must be a quantum system, too. It circumvents the difficulties to find measuring devices for something we know nothing about.

    “For our experiments, we used proton spins of ‘brain water’ as the known system. ‘Brain water’ builds up naturally as fluid in our brains and the proton spins can be measured using MRI (Magnetic Resonance Imaging). Then, by using a specific MRI design to seek entangled spins, we found MRI signals that resemble heartbeat-evoked potentials, a form of EEG signals. EEGs measure electrical brain currents, which some people may recognize from personal experience or simply from watching hospital dramas on TV.”

    Electrophysiological potentials like the heartbeat-evoked potentials are normally not detectable with MRI and the scientists believe they could only observe them because the nuclear proton spins in the brain were entangled.

    “If entanglement is the only possible explanation here then that would mean that brain processes must have interacted with the nuclear spins, mediating the entanglement between the nuclear spins. As a result, we can deduce that those brain functions must be quantum.

    “Because these brain functions were also correlated to short-term memory performance and conscious awareness, it is likely that those quantum processes are an important part of our cognitive and conscious brain functions.

    “Quantum brain processes could explain why we can still outperform supercomputers when it comes to unforeseen circumstances, decision making, or learning something new. Our experiments performed only 50 meters away from the lecture theater, where Schrödinger presented his famous thoughts about life, may shed light on the mysteries of biology, and on consciousness which scientifically is even harder to grasp.”



    Gassho, J

    stlah

    Leave a comment:


  • Jundo
    replied
    I predict that this may be a great discovery ... or that it won't be ...

    Scientists Use Machine Learning To Peer Into the Future

    Chaotic physical processes are now easier to predict thanks to a new algorithm.


    While the past may be a fixed and unchangeable point, machine learning can sometimes make predicting the future easier.

    Researchers at The Ohio State University have recently discovered a new way to predict the behavior of spatiotemporal chaotic systems, such as changes in Earth’s weather, that are particularly difficult for scientists to forecast using a new type of machine learning technique called next generation reservoir computing.

    The research, which was recently published in the journal Chaos: An Interdisciplinary Journal of Nonlinear Science, makes use of a brand-new, highly efficient algorithm that, when combined with next-generation reservoir computing, can learn spatiotemporal chaotic systems in a fraction of the time required by traditional machine learning algorithms.

    Researchers put their method to the test by predicting the behavior of an atmospheric weather model, a challenging problem that has been researched extensively in the past. The Ohio State team’s algorithm is more accurate and needs 400 to 1,250 times less training data to generate better predictions than its rival, traditional machine learning algorithms that can do the same tasks. They used a laptop running Windows 10 to make predictions in a fraction of a second, which is roughly 240,000 times faster than conventional machine learning algorithms. Their method is also less computationally expensive; whereas solving complex computing problems previously required a supercomputer.

    “This is very exciting, as we believe it’s a substantial advance in terms of data processing efficiency and prediction accuracy in the field of machine learning,” said Wendson De Sa Barbosa, lead author and a postdoctoral researcher in physics at Ohio State. He said that learning to predict these extremely chaotic systems is a “physics grand challenge,” and understanding them could pave the way to new scientific discoveries and breakthroughs.

    Gassho, J

    stlah

    Leave a comment:


  • Jundo
    replied
    Our first baby steps ...


    A new study demonstrates how the pelvis evolved for upright walking.


    If evolutionary biologist Terence D. Capellini were to rank the body parts that define us as human, the pelvis would be towards the top.

    After all, thanks to its design, humans can walk upright on two legs (unlike our primate cousins) and mothers can give birth to children with huge heads (therefore big brains). The pelvis is anatomically well-understood, but when it comes to how and when this very essential structure takes form throughout development, our understanding begins to falter.

    ... The study shows that many of the features essential for human walking and birth form around the 6- to 8-week mark during pregnancy. This includes key pelvic features unique to humans, like its curved and basin-like shape. The formation happens while bones are still cartilage so they can easily, curve, rotate, expand, and grow.

    The researchers also discovered that when other cartilage in the body starts to transform into bone, the developing pelvic region remains as cartilage for a longer period of time, allowing it to mature properly.

    “There appears to be a stalling that happens and this stalling allows the cartilage to still grow, which was pretty interesting to find and surprising,” Capellini said. “I call it a zone of protection.”

    The researchers used RNA sequencing to determine which genes in the area are actively triggering pelvic formation and slowing ossification, which usually converts softer cartilage to hard bone. They discovered hundreds of genes that are turned either on or off throughout the 6- to 8-week period to form the ilium in the pelvis, which is the largest and uppermost bone of the hip with blade-like structures that curve and rotate into a basin to support walking on two legs.

    Compared to chimpanzees and gorillas, the shorter and wider reorientation of our pelvic blades makes it so humans don’t have to shift the mass of our weight forward and use our knuckles to walk or balance more comfortably. It also helps increase the size of the birth canal. Apes on the other hand have much narrower birth canals and more elongated ilium bones.

    https://scitechdaily.com/why-do-huma...al-the-secret/
    And a fascinating look at our stellar face, and its changes ...

    NASA’s NEOWISE Space Telescope Takes 12-Year Time-Lapse Movie of Entire Sky

    NASA’s Near-Earth Object Wide Field Infrared Survey Explorer, or NEOWISE, spacecraft completes one trip halfway around the Sun every six months, taking images in all directions. Once stitched together, those images form an “all-sky” map showing the location and brightness of hundreds of millions of objects. Using 18 all-sky maps produced by the spacecraft (with the 19th and 20th to be released in March 2023), astronomers have constructed what is essentially a time-lapse movie of the sky, revealing changes that span a decade.

    Each all-sky map is a tremendously valuable resource for astronomers by itself. However, when viewed in sequence as a time-lapse, they serve as an even more powerful tool for attempting to unlock the secrets of the universe. Comparing the maps can reveal distant objects that have changed position or brightness over time. This is known as time-domain astronomy.

    https://scitechdaily.com/nasas-neowi...of-entire-sky/

    Gassho, J

    stlah

    Leave a comment:


  • Jundo
    replied
    Our common root with mice and elephants ...

    Scientists Reconstruct the Genome of the 180-Million-Year-Old Common Ancestor of All Mammals

    From a platypus to a blue whale, all living mammals today are descended from a common ancestor that existed some 180 million years ago. Although we don’t know a lot about this animal, a global team of experts has recently computationally reconstructed the organization of its genome. The findings were recently published in the journal Proceedings of the National Academy of Sciences.

    “Our results have important implications for understanding the evolution of mammals and for conservation efforts,” said Harris Lewin, distinguished professor of evolution and ecology at the University of California, Davis, and senior author on the paper. ... The researchers identified 1,215 blocks of genes that appear on the same chromosome in the same order across all 32 genomes. Damas said that these building blocks of all mammal genomes include genes that are essential for the development of a normal embryo. ... “This remarkable finding shows the evolutionary stability of the order and orientation of genes on chromosomes over an extended evolutionary timeframe of more than 320 million years,” Lewin said.

    In contrast, regions between these conserved blocks contained more repetitive sequences and were more prone to breakages, rearrangements, and sequence duplications, which are major drivers of genome evolution. ... The researchers were able to follow the ancestral chromosomes forward in time from the common ancestor. They found that the rate of chromosome rearrangement differed between mammal lineages. For example, in the ruminant lineage (leading to modern cattle, sheep, and deer) there was an acceleration in rearrangement 66 million years ago when an asteroid impact killed off the dinosaurs and led to the rise of mammals.


    Gassho, J

    stlah

    Leave a comment:


  • Jundo
    replied
    Using our brains ... or parts of them anyway ...

    Watch Live Human Brain Cells in a Dish Learn To Play Pong

    Scientists have shown for the first time that 800,000 brain cells living in a dish can perform goal-directed tasks. In this case, they played the simple tennis-like computer game, Pong. The results of the Melbourne-led study are published today (October 12) in the journal Neuron. ... “We have shown we can interact with living biological neurons in such a way that compels them to modify their activity, leading to something that resembles intelligence,” says lead author Dr. Brett Kagan. ... Although researchers have been able to mount neurons on multi-electrode arrays and read their activity for some time now, this is the first time that cells have been stimulated in a structured and meaningful way. “In the past, models of the brain have been developed according to how computer scientists think the brain might work,” Kagan says. “That is usually based on our current understanding of information technology, such as silicon computing.

    “But in truth, we don’t really understand how the brain works.”

    By constructing a living model brain from basic structures in this way, scientists will be able to experiment using real brain function rather than flawed analogous models such as a computer.

    For example, Kagan and his team will next experiment to see what effect alcohol has when introduced to DishBrain.

    “We’re trying to create a dose-response curve with ethanol – basically get them ‘drunk’ and see if they play the game more poorly, just as when people drink,” says Kagan. “This new capacity to teach cell cultures to perform a task in which they exhibit sentience – by controlling the paddle to return the ball via sensing – opens up new discovery possibilities which will have far-reaching consequences for technology, health, and society,” ...

    ... Electrodes on the left or right of one array were fired to tell Dishbrain which side the ball was on, while the distance from the paddle was indicated by the frequency of signals. Feedback from the electrodes taught DishBrain how to return the ball, by making the cells act as if they themselves were the paddle.

    “We’ve never before been able to see how the cells act in a virtual environment,” says Kagan. “We managed to build a closed-loop environment that can read what’s happening in the cells, stimulate them with meaningful information and then change the cells in an interactive way so they can actually alter each other.”



    [Below is a visual representation of the simulated Pong environment where neuron activity is reflected in the tiles growing in height.]

    ... and ... people sometimes think like rats ... and rats now think like people ...

    Human ‘mini-brains’ implanted in rats prompt excitement — and concern

    Miniature human brain-like structures transplanted into rats can send signals and respond to environmental cues picked up by the rats’ whiskers, according to a study1. This demonstration that neurons grown from human stem cells can interface with nerve cells in live rodents could lead to a way to test therapies for human brain disorders. ...

    ... neuroscientist Sergiu Pasca at Stanford University in California and his colleagues grew the structures from human stem cells and then injected them into the brains of newborn rat pups, with the expectation that the human cells would grow along with the rats’ own cells. The team placed the organoids in a brain region called the somatosensory cerebral cortex, which receives signals from the rats’ whiskers and other sensory organs and then passes them along to other brain regions that interpret the signals. Human brain cells mature much more slowly than rat cells, so the researchers had to wait for more than six months for the organoids to become fully integrated into the rat brains. But when they examined the animals’ brains at the end of that time, they saw that the integration had been so successful that it was almost like adding “another transistor to a circuit”, Pasca said at a 10 October press conference. ...

    ... In their report, published in Nature on 12 October1, the researchers describe how they genetically engineered the neurons in the organoids to fire when stimulated with light from a fibre-optic cable embedded in the rats’ brains. The team trained the rats to lick a spout to receive water while the light was switched on. Afterwards, when the researchers shone the light on the hybrid brains, the rats were prompted to lick the spout, meaning that the human cells had become integrated well enough to help drive the animals’ behaviour. Furthermore, when the researchers tweaked the rats’ whiskers, they found that the human cells in the sensory cortex fired in response, suggesting that the cells were able to pick up sensory information. ...

    ... Some of the challenges are ethical. People are concerned that creating rodent–human hybrids could harm the animals, or create animals with human-like brains. Last year, a panel organized by the US National Academies of Sciences, Engineering, and Medicine released a report concluding that human brain organoids are still too primitive to become conscious, attain human-like intelligence or acquire other abilities that might require legal regulation. Pasca says that his team’s organoid transplants didn’t cause problems such as seizures or memory deficits in the rats, and didn’t seem to change the animals’ behaviour significantly.

    But Arlotta, a member of the National Academies panel, says that problems could arise as science advances. “We can’t just discuss it once and let it be,” she says. She adds that concerns about human organoids need to be weighed against the needs of people with neurological and psychiatric disorders. Brain organoids and human–animal hybrid brains could reveal the mechanisms underlying these illnesses, and allow researchers to test therapies for conditions such as schizophrenia and bipolar disorder. “I think we have a responsibility as a society to do everything we can,” Arlotta says.



    [PICTURE: Researchers have transplanted a human brain organoid (bright green) into the brain of a newborn rat pup, creating hybrid brains in which the neurons interface.]

    Gassho, J
    Last edited by Jundo; 10-13-2022, 01:47 AM.

    Leave a comment:


  • Jundo
    replied
    It is amazing what we can do with Photoshop ...

    Science enthusiasts have processed the new JunoCam images of Jupiter’s icy moon, with results that are out of this world.

    Citizen scientists have furnished unique perspectives of the recent close flyby of Jupiter’s icy moon Europa by NASA’s Juno spacecraft. By processing raw images from JunoCam, the spacecraft’s public-engagement camera, members of the general public have created deep-space portraits of the Jovian moon that are not only spectacular, but also worthy of further scientific investigation.

    ... Europa is the solar system’s sixth-largest moon with about 90% of the equatorial diameter of Earth’s moon. Scientists are confident a salty ocean lies below a miles-thick ice shell, sparking questions about the potential habitability of the ocean. In the early 2030s, NASA’s Europa Clipper spacecraft will arrive and strive to answer these questions about Europa’s habitability. The data from the Juno flyby provides a preview of what that mission will reveal

    ... The images and spectra of Europa, published in the Planetary Science Journal, reveal that Europa’s crust is mainly composed of frozen water ice with non-ice materials contaminating the surface. Oliver King from the University of Leicester School of Physics and Astronomy said: “We mapped the distributions of the different materials on the surface, including sulphuric acid frost which is mainly found on the side of Europa that is most heavily bombarded by the gases surrounding Jupiter.” “The modeling found that there could be a variety of different salts present on the surface, but suggested that infrared spectroscopy alone is generally unable to identify which specific types of salt are present.” ... With this additional data about Europa’s geology, Juno’s observations will benefit future missions to the Jovian moon, including NASA’s Europa Clipper. That mission, set to launch in 2024, will study Europa’s atmosphere, surface, and interior. Its main science goal will be to determine whether there are locations below the moon’s surface that could support life.

    https://scitechdaily.com/enhance-cit...om-nasas-juno/



    Gassho, J

    stlah
    Last edited by Jundo; 10-12-2022, 12:17 AM.

    Leave a comment:


  • Jundo
    replied
    Where our Milky Way Galaxy puts its old used stars out for recycling ...

    The Milky Way galaxy has a graveyard of dead stars that stretches three times the height of the galaxy, according to new research. Astronomers found the ancient stellar remnants when they mapped this “galactic underworld” for the first time.

    Our galaxy, which formed about 13 billion years ago, has been the home of billions of stars. Over time, many of these massive objects have collapsed into dense remnants.

    When a star more than eight times larger than the sun burns through its elements and collapses, the outer layers of the star explode in a supernova. Meanwhile, the stellar core condenses into either a neutron star or black hole. ... The very supernova explosions that triggered the collapse of the stars actually kicked them out into interstellar space. Researchers determined that 30% of those stellar remnants have been kicked out of the galaxy completely, according to their study published in the latest issue of the journal Monthly Notices of the Royal Astronomical Society.

    The research team was able to map where the stellar remains rest within and around our galaxy by recreating the life cycle of the ancient stars. “One of the problems for finding these ancient objects is that, until now, we had no idea where to look,” said study coauthor Peter Tuthill, professor at the School of Physics and director of the Sydney Institute for Astronomy at The University of Sydney in Australia, in a statement.

    ... “Almost all the remnants ever formed are still out there, sliding like ghosts through interstellar space,” Sweeney said.

    The new map includes where the stars were born within the Milky Way, where they exploded and their eventual resting places.
    Milky Way WITHOUT showing the "Galactic Underworld" ...


    Comparing the Milky Way’s current appearance with the new model of its stellar necropolis shows striking differences. The galaxy’s characteristic spiral arms seem to disappear beneath all of the supernova kicks that wash them out.

    The “galactic underworld” also appears taller and more puffy than the Milky Way because the supernova kicks pushed the remnants into a kind of halo formation around the galaxy.
    Milky Way WITH the "Galactic Underworld" ...


    Gassho, J

    stlah

    Leave a comment:

Working...