Unprecedented Detail: Researchers Capture How Genes Fold and Work
The new technique is “like upgrading from the Hubble to the James Webb.”
A new imaging technique captures the three-dimensional architecture of the human genome with unprecedented detail, showing how individual genes fold at the level of nucleosomes, the fundamental units constituting the genome’s three-dimensional architecture.
The technology, which was created by Barcelona-based researchers at the Centre for Genomic Regulation (CRG) and the Institute for Research in Biomedicine (IRB Barcelona), combines high-resolution microscopy with sophisticated computer modeling. It is the most comprehensive technique to date for studying the shape of genes.
The new technique allows researchers to create and digitally navigate three-dimensional models of genes, seeing not just their architecture but also information on how they move or how flexible they are.
Comparison using a conventional microscope (left) to visualize the structure of the NANOG gene, which shows up as a bright green spot vs. using MiOS (right) which can image individual genes. MiOS is roughly ten times better in resolution and also details critical aspects of the structure that are not discernible using conventional methods.
https://scitechdaily.com/unprecedent...fold-and-work/
The new technique is “like upgrading from the Hubble to the James Webb.”
A new imaging technique captures the three-dimensional architecture of the human genome with unprecedented detail, showing how individual genes fold at the level of nucleosomes, the fundamental units constituting the genome’s three-dimensional architecture.
The technology, which was created by Barcelona-based researchers at the Centre for Genomic Regulation (CRG) and the Institute for Research in Biomedicine (IRB Barcelona), combines high-resolution microscopy with sophisticated computer modeling. It is the most comprehensive technique to date for studying the shape of genes.
The new technique allows researchers to create and digitally navigate three-dimensional models of genes, seeing not just their architecture but also information on how they move or how flexible they are.

https://scitechdaily.com/unprecedent...fold-and-work/
Astronomers Discover Important New Information Regarding Star Formation
An important new hint regarding how galaxies halt intense episodes of star formation has been found by astronomers using the Karl G. Jansky Very Large Array (VLA) of the National Science Foundation. Their recent research on the nearby galaxy M33 suggests that fast cosmic ray electrons can generate winds that blow away the gas required for the formation of new stars.
As galaxies evolve over time, these winds are what cause the star formation rate to slow down. However, the primary sources of such winds have been attributed to material jets powered by black holes and shock waves from supernova explosions. Cosmic rays were assumed to be small contributors, especially in galaxies with prolific star formation, such as M33.
“We have seen galactic winds driven by cosmic rays in our own Milky Way and the Andromeda galaxy, which have much weaker rates of star formation, but not before in a galaxy such as M33,” said Fatemah Tabatabaei, of the Institute for Research in Fundamental Sciences in Iran.
M33 is a spiral galaxy that is almost 3 million light-years distant and is a member of the Local Group of galaxies, which also contains the Milky Way. Tabatabaei and an international team of scientists made detailed, multi-wavelength VLA observations of M33. Additionally, they made use of information gathered from earlier observations made with the VLA, the German Effelsberg radio telescope, millimeter-wave, visible-light, and infrared telescopes.
Stars much larger than our Sun speed through their life cycles, eventually exploding as supernovae. Cosmic rays are produced when explosive shock waves accelerate particles almost to the speed of light. If there are enough of these cosmic rays, pressure can be created that drives winds that transport away the gas required for star formation.
https://scitechdaily.com/astronomers...tar-formation/
An important new hint regarding how galaxies halt intense episodes of star formation has been found by astronomers using the Karl G. Jansky Very Large Array (VLA) of the National Science Foundation. Their recent research on the nearby galaxy M33 suggests that fast cosmic ray electrons can generate winds that blow away the gas required for the formation of new stars.
As galaxies evolve over time, these winds are what cause the star formation rate to slow down. However, the primary sources of such winds have been attributed to material jets powered by black holes and shock waves from supernova explosions. Cosmic rays were assumed to be small contributors, especially in galaxies with prolific star formation, such as M33.
“We have seen galactic winds driven by cosmic rays in our own Milky Way and the Andromeda galaxy, which have much weaker rates of star formation, but not before in a galaxy such as M33,” said Fatemah Tabatabaei, of the Institute for Research in Fundamental Sciences in Iran.
M33 is a spiral galaxy that is almost 3 million light-years distant and is a member of the Local Group of galaxies, which also contains the Milky Way. Tabatabaei and an international team of scientists made detailed, multi-wavelength VLA observations of M33. Additionally, they made use of information gathered from earlier observations made with the VLA, the German Effelsberg radio telescope, millimeter-wave, visible-light, and infrared telescopes.
Stars much larger than our Sun speed through their life cycles, eventually exploding as supernovae. Cosmic rays are produced when explosive shock waves accelerate particles almost to the speed of light. If there are enough of these cosmic rays, pressure can be created that drives winds that transport away the gas required for star formation.
https://scitechdaily.com/astronomers...tar-formation/
Groundbreaking New Technology Allows People To Listen to Music Through Touch
A ground-breaking prototype developed by experts from the Department of Electronics at the University of Malaga and members of the R&D group “Electronics for Instrumentation and Systems,” will allow those with hearing loss to listen to music through the sense of touch.
It consists of an audio-tactile algorithm that transforms monophonic music into tangible stimuli based on vibration utilizing “tactile illusions.” According to the researchers, “It’s like ‘hacking’ the nervous system to receive a different response to the real stimulus sent.”
“What we want to achieve in the long term is for people who do not hear to be able to ‘listen’ to music”, assures researcher Paul Remache, the main author of this paper, who insists on the power of music to influence mood, as well as its possibilities as a therapy for mental disorders and treatment of pain.
The researchers predict that this will lead to a portable terminal that may be brought to a concert since this prototype will be easily transferable to technological devices like smartphones.
https://scitechdaily.com/groundbreak...through-touch/
A ground-breaking prototype developed by experts from the Department of Electronics at the University of Malaga and members of the R&D group “Electronics for Instrumentation and Systems,” will allow those with hearing loss to listen to music through the sense of touch.
It consists of an audio-tactile algorithm that transforms monophonic music into tangible stimuli based on vibration utilizing “tactile illusions.” According to the researchers, “It’s like ‘hacking’ the nervous system to receive a different response to the real stimulus sent.”
“What we want to achieve in the long term is for people who do not hear to be able to ‘listen’ to music”, assures researcher Paul Remache, the main author of this paper, who insists on the power of music to influence mood, as well as its possibilities as a therapy for mental disorders and treatment of pain.
The researchers predict that this will lead to a portable terminal that may be brought to a concert since this prototype will be easily transferable to technological devices like smartphones.
https://scitechdaily.com/groundbreak...through-touch/
Disabled man joins European Space Agency's astronaut programme
- The European Space Agency on Wednesday named the first ever "parastronaut" in a major step towards allowing people with physical disabilities to work and live in space.
The 22-nation agency said it had selected former British Paralympic sprinter John McFall as part of a new generation of 17 recruits picked for astronaut training.
He will take part in a feasibility study designed to allow ESA to assess the conditions needed for people with disabilities to take part in future missions. ... ESA posted openings last year for people fully capable of passing its usual stringent psychological, cognitive and other tests who are only prevented from becoming astronauts due to the constraints of existing hardware in light of their disability. ...
"Better representation of disabled people in influential roles will really help improve attitudes and break down the barriers that many disabled people face today," the charity's Head of Communications, Alison Kerry, said.
Following a motorcycle accident that led to his right leg being amputated at the age of 19, McFall went on to win the 100-metres Bronze Medal at the Beijing Paralympic Games in 2008.
The 31-year-old doctor will help ESA engineers design changes in hardware needed to open professional spaceflight to a wider group of qualified candidates, the agency said.
- The European Space Agency on Wednesday named the first ever "parastronaut" in a major step towards allowing people with physical disabilities to work and live in space.
The 22-nation agency said it had selected former British Paralympic sprinter John McFall as part of a new generation of 17 recruits picked for astronaut training.
He will take part in a feasibility study designed to allow ESA to assess the conditions needed for people with disabilities to take part in future missions. ... ESA posted openings last year for people fully capable of passing its usual stringent psychological, cognitive and other tests who are only prevented from becoming astronauts due to the constraints of existing hardware in light of their disability. ...
"Better representation of disabled people in influential roles will really help improve attitudes and break down the barriers that many disabled people face today," the charity's Head of Communications, Alison Kerry, said.
Following a motorcycle accident that led to his right leg being amputated at the age of 19, McFall went on to win the 100-metres Bronze Medal at the Beijing Paralympic Games in 2008.
The 31-year-old doctor will help ESA engineers design changes in hardware needed to open professional spaceflight to a wider group of qualified candidates, the agency said.
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