3 paralyzed men can walk again after getting electrode implant
The device stimulates specific spinal nerves.
Three men with paralyzing spinal cord injuries can now stand, walk and cycle after electrodes were implanted into their spinal cords.
The electrodes deliver electrical pulses to specific regions of the spinal cord and thus activate muscles in the trunk and legs, according to a new study, published Monday (Feb. 7) in the journal Nature Medicine. The soft, flexible device lies directly on top of the spinal nerves, beneath the vertebrae, and can be controlled wirelessly with software, operated from a tablet, and a handheld clicker.
The software communicates with a pacemaker-like device in the abdomen, which then directs the activity of the nerve-bound electrodes on the spinal cord. So, with the tap of a touch screen, the user of the implant can prompt their device to generate a precise pattern of stimulation. These stimulation patterns translate to patterns of muscle activity, allowing the user to walk, cycle, or swim, for instance. Users can also manually switch between these stimulation patterns with their clicker. "All three patients were able to stand, walk, pedal, swim and control their torso movements in just one day, after their implants were activated ..."
After the initial implantation, the patients underwent extensive training to get used to using the device and regain muscle mass and motor control, co-senior author Dr. Jocelyne Bloch, an associate professor of neurosurgery at Lausanne University Hospital, told The Guardian. "It was not perfect at the beginning, but they could train very early to have a more fluid gait," she said. Eventually, the patients progressed from using the implants only in a controlled lab setting to using them out and about in their daily lives.
After four months of training, one patient, Michel Roccati, was able to walk about 0.6 mile (1 kilometer) outside the lab and without stopping, with only a frame for balance, AFP reported. He can now continuously stand for about two hours. Like the other participants in the trial, Roccati has a complete spinal cord injury, meaning the nerves below his site of injury cannot communicate with the brain at all. He was injured in a motorcycle accident in 2019 and lost both feeling and motor control in his legs.
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The team is also investigating whether a similar stimulator could be implanted directly into the motor cortex, a key region of the brain for controlling voluntary movement, Courtine told NBC News. Such a device could allow people with paralysis to direct their movements without the aid of a tablet or clicker.
https://www.livescience.com/spinal-i...fter-paralysis
The device stimulates specific spinal nerves.
Three men with paralyzing spinal cord injuries can now stand, walk and cycle after electrodes were implanted into their spinal cords.
The electrodes deliver electrical pulses to specific regions of the spinal cord and thus activate muscles in the trunk and legs, according to a new study, published Monday (Feb. 7) in the journal Nature Medicine. The soft, flexible device lies directly on top of the spinal nerves, beneath the vertebrae, and can be controlled wirelessly with software, operated from a tablet, and a handheld clicker.
The software communicates with a pacemaker-like device in the abdomen, which then directs the activity of the nerve-bound electrodes on the spinal cord. So, with the tap of a touch screen, the user of the implant can prompt their device to generate a precise pattern of stimulation. These stimulation patterns translate to patterns of muscle activity, allowing the user to walk, cycle, or swim, for instance. Users can also manually switch between these stimulation patterns with their clicker. "All three patients were able to stand, walk, pedal, swim and control their torso movements in just one day, after their implants were activated ..."
After the initial implantation, the patients underwent extensive training to get used to using the device and regain muscle mass and motor control, co-senior author Dr. Jocelyne Bloch, an associate professor of neurosurgery at Lausanne University Hospital, told The Guardian. "It was not perfect at the beginning, but they could train very early to have a more fluid gait," she said. Eventually, the patients progressed from using the implants only in a controlled lab setting to using them out and about in their daily lives.
After four months of training, one patient, Michel Roccati, was able to walk about 0.6 mile (1 kilometer) outside the lab and without stopping, with only a frame for balance, AFP reported. He can now continuously stand for about two hours. Like the other participants in the trial, Roccati has a complete spinal cord injury, meaning the nerves below his site of injury cannot communicate with the brain at all. He was injured in a motorcycle accident in 2019 and lost both feeling and motor control in his legs.
...
The team is also investigating whether a similar stimulator could be implanted directly into the motor cortex, a key region of the brain for controlling voluntary movement, Courtine told NBC News. Such a device could allow people with paralysis to direct their movements without the aid of a tablet or clicker.
https://www.livescience.com/spinal-i...fter-paralysis


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