Quite strange!
Gassho, Tokan
satlah
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Ok, this is one of the strangest stories I have heard in awhile ...
Journalist says he had a creepy encounter with new tech that left him unable to sleep ... New York Times technology columnist Kevin Roose has early access to new features in Microsoft's search engine Bing that incorporates artificial intelligence. Roose says the new chatbot tried to get him to leave his wife.
Gassho, J
stlahLeave a comment:
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Now, I need GPS to find where I put my glasses!
AI fixes DNA ...Augmented Reality GPS Navigation in a Smart Contact Lens – Made With 3D Printer!
Core 3D printing process technology for smart contact lenses that can implement augmented reality (AR)-based navigation has been developed by Dr. Seol Seung-Kwon’s Smart 3D Printing Research Team at the Korea Electrotechnology Research Institute (KERI) and Professor Lim-Doo Jeong’s team at Ulsan National Institute of Science and Technology (UNIST).
A smart contact lens is a product attached to the human eye like a normal lens and provides various information. Research on the lens is being conducted mainly on diagnosing and treating health. Recently, Google and others are developing smart contact lenses for displays that can implement AR. Still, many obstacles to commercialization exist due to severe technical challenges.
... The main expected application area is navigation. Simply by wearing a lens, navigation unfolds in front of a person’s eyes through AR. Games such as the popular ‘Pokemon Go’ can also be enjoyed with smart contact lenses, not smartphones.
Dr. Seol Seung-Kwon’s of KERI said, “Our achievement is a development of 3D printing technology that can print functional micro-patterns on non-planner substrate that can commercialize advanced smart contact lenses to implement AR.” He added, “It will greatly contribute to the miniaturization and versatility of AR devices.”
MOJO Vision is another company working on contact augmented reality ...
Gassho, JMachine Learning Helps Design the Best Fix for a Given Genetic Flaw
Researchers at the Wellcome Sanger Institute have developed a new tool to predict the chances of successfully inserting a gene-edited sequence of DNA into the genome of a cell, using a technique known as prime editing. An evolution of CRISPR-Cas9 gene editing technology, prime editing has huge potential to treat genetic diseases in humans, from cancer to cystic fibrosis. But thus far, the factors determining the success of edits are not well understood.
The study, published today (February 16, 2023) in the journal Nature Biotechnology, assessed thousands of different DNA sequences introduced into the genome using prime editors. These data were then used to train a machine learning algorithm to help researchers design the best fix for a given genetic flaw, which promises to speed up efforts to bring prime editing into the clinic.
... Developed in 2012, CRISPR-Cas9 was the first easily programmable gene editing technology. These ‘molecular scissors’ enabled researchers to cut DNA at any position in the genome in order to remove, add or alter sections of the DNA sequence. The technology has been used to study which genes are important for various conditions, from cancer to rare diseases, and to develop treatments that fix or turn off harmful mutations or genes.
Base editors were an innovation expanding on CRISPR-Cas9 and were called ‘molecular pencils’ for their ability to substitute single bases of DNA. The latest gene editing tools, created in 2019, are called prime editors. Their ability to perform search and replace operations directly on the genome with a high degree of precision has led to them being dubbed ‘molecular word processors’.
The ultimate aim of these technologies is to correct harmful mutations in people’s genes. Over 16,000 small deletion variants – where a small number of DNA bases have been removed from the genome – have been causally linked to disease. This includes cystic fibrosis, where 70 percent of cases are caused by the deletion of just three DNA bases. In 2022, base edited T-cells were successfully used to treat a patient’s leukemia, where chemotherapy and bone marrow transplant had failed. ...
... Jonas Koeppel, first author of the study from the Wellcome Sanger Institute, said: “The variables involved in successful prime edits of the genome are many, but we’re beginning to discover what factors improve the chances of success. Length of sequence is one of these factors, but it’s not as simple as the longer the sequence the more difficult it is to insert. We also found that one type of DNA repair prevented the insertion of short sequences, whereas another type of repair prevented the insertion of long sequences.” ...
... Juliane Weller, a first author of the study from the Wellcome Sanger Institute, said: “Put simply, several different combinations of three DNA letters can encode for the same amino acid in a protein. That’s why there are hundreds of ways to edit a gene to achieve the same outcome at the protein level. By feeding these potential gene edits into a machine learning algorithm, we have created a model to rank them on how likely they are to work. We hope this will remove much of the trial and error involved in prime editing and speed up progress considerably." ...
https://scitechdaily.com/acceleratin...-genetic-flaw/
stlahLast edited by Jundo; 02-17-2023, 03:51 AM.Leave a comment:
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Combining new technologies to solve an ancient disease ...
Even if this is not exactly what happened, something just as fantastic seems to have happened. We are space creatures, fallen to earth ...Lasers, robots, and tiny electrodes are transforming treatment of severe epilepsy
... There are a growing number of patients like Tom. Their stories show how new technology is changing the way doctors assess and treat drug-resistant epilepsy, which affects more than a quarter of the roughly 3 million people in the U.S. with the disorder.
Technological advances include not only tiny electrodes and lasers, but MRI machines that provide high-resolution images during surgery, and implanted devices that can stop a seizure in its tracks.
"We help the vast majority of patients we treat quite significantly with a combination of these technologies," says Dr. Sharona Ben-Haim, the neurosurgeon at UCSD who operated on Tom. ...
https://www.npr.org/sections/health-...evere-epilepsy
AND THIS IS JUST SUPER COOLLLLLLLLLLL!!!!!Unraveling the Origins of the Building Blocks of Life: The Role of Interstellar Clouds
A recent study led by Dr. Danna Qasim, a research scientist at the Southwest Research Institute, suggests that the conditions within interstellar clouds may have had a substantial impact on the presence of key building blocks of life in the solar system. “Carbonaceous chondrites, some of the oldest objects in the universe, are meteorites that are thought to have contributed to the origins of life. They contain several different molecules and organic substances, including amines and amino acids, which are key building blocks of life that were critical to creating life on Earth. These substances are necessary to create proteins and muscle tissue,” Qasim said.
Most meteorites are pieces of asteroids that shattered in the asteroid belt, situated between Mars and Jupiter, a long time ago. These fragments orbit the Sun for extended periods, potentially millions of years, before they collide with Earth.
One of the questions Qasim and others are trying to answer is how amino acids got into the carbonaceous chondrites in the first place.
DO NOT MISS THIS: From 7:00 mark to 10:30 ....... Nina Kraus, PhD, is director of the Auditory Neuroscience Lab (Brainvolts) at Northwestern University. ...
SHAPIRO: So your research can actually show us what the brain experiences when it encounters sound. How does that work?
KRAUS: Absolutely. As I'm talking to you now, the neurons in your brain that respond to sound are producing electricity. And with scalp electrodes, we can measure that electricity. I can then sonify it so that we can listen to what your brain produced when it was listening to whatever it was that you were listening to. And what is remarkable is that when we play back the brain's response to sound, it will actually physically resemble the sound that stimulated the brain in the first place.
SHAPIRO: OK, let's do it. What do you want to play for us?
KRAUS: So here is a person listening to "Amazing Grace." So here's the sound that we're hearing.
(SOUNDBITE OF MUSIC)
KRAUS: And this is the response that we captured as they were listening to this particular clip of "Amazing Grace."
(SOUNDBITE OF MUSIC)
KRAUS: Pretty recognizable, right? So we have so much to work with. We can listen to this person's response to sound, so you can imagine we can compare different kinds of people and different kinds of brains. ...
Mind reading just around the corner??
Gassho, J
stlahLeave a comment:
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Hmmm.
Off to another adventure ... a European vacation ...Scientists Discover Common Brain Network for Psychiatric Illnesses
Nearly one in five adults in the United States is affected by psychiatric disorders such as schizophrenia and depression. Additionally, about half of patients diagnosed with a psychiatric illness also have symptoms of another disorder. This overlap has led researchers to believe that there may be a single neurobiological explanation for various psychiatric illnesses. A team of researchers from Brigham and Women’s Hospital, a member of the Mass General Brigham healthcare system, studied four existing neurological and psychiatric datasets and pinpointed a network of brain areas underlying psychiatric illnesses. The results of the study were recently published in the journal Nature Human Behavior.
... The researchers began by analyzing a set of structural brain data from over 15,000 healthy controls as well as patients diagnosed with schizophrenia, bipolar disorder, depression, addiction, obsessive-compulsive disorder, or anxiety. They found gray matter decreases in anterior cingulate and insula, two brain regions commonly associated with psychiatric illness. However, only a third of studies showed gray matter decreases in these brain regions. Additionally, neurodegenerative diseases also showed gray matter decreases in these same regions.
... Instead, their analyses point to the posterior parietal cortex as the brain network node most likely to be causally associated with psychiatric illness.
By identifying a significant, sensitive, and specific transdiagnostic network for psychiatric illness, the team has opened up a number of possible new directions for follow-up studies, including analyzing existing fMRI datasets to see if neural activation patterns follow the same circuit and investigating circuit-based differences across psychiatric disorders. Taylor also plans on using Transcranial Magnetic Stimulation (TMS) to modulate the network, specifically using the posterior parietal region as a target.
“Psychiatric disorders are brain disorders, and now we’re just beginning to have the tools to study and modulate their underlying circuitry,” said Taylor. “There may be more in common across these disorders than we originally thought.”
https://scitechdaily.com/scientists-...ric-illnesses/
Gassho, JA grand odyssey of exploration is about to begin. Humankind’s next bold mission to the outer Solar System, ESA’s Jupiter Icy Moons Explorer, Juice, is poised to explore giant planet Jupiter and its largest moons.
These intriguing worlds have piqued our curiosity ever since Galileo first raised his telescope to the planet and discovered its four largest moons: Io, Europa, Ganymede, and Callisto, three of which are thought to harbor underground oceans.
Early space probes visiting the Jovian system have raised more questions than answers. But thanks to Juice, many of those answers are now within reach. ESA is launching the spacecraft in April 2023 on an eight-year journey to the distant planet.
... The mission aims to explore the emergence of habitable worlds around gas giants, using the Jupiter system as a model for the many giant planets found orbiting other stars. It will make detailed observations of the giant gas planet and its three large ocean-bearing moons – Ganymede, Callisto, and Europa – with a comprehensive suite of remote sensing, geophysical, and in situ instruments.
stlahLeave a comment:
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This is what earth will look like in ??zillion years as our red dwarf (sun) expands and envelops us. (ref: what we see in our desserts to date; also, life is impermanence) I don't plan on being around to see this happen.
gassho, Shokai
stlahLast edited by Shokai; 02-14-2023, 03:04 AM.Leave a comment:
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Lakefront property ... on Mars ...
HUMANganese ...NASA rover finds ‘clearest evidence yet’ of an ancient lake on Mars
In the foothills of a Martian mountain, NASA’s Curiosity rover found stunning new evidence of an ancient lake in the form of rocks etched with the ripples of waves — and the telltale signs appeared in an unlikely place.
The rover is traversing an area of Mars called the “sulfate-bearing unit” that researchers previously thought would only show evidence of mere trickles of water, as scientists believed the rocks there formed as the surface of the red planet was drying out. Instead, the rover found some of the clearest evidence yet of ancient waters. ... The sulfate-bearing unit is a region previously identified by the Mars Reconaissance Orbiter as containing salty mineral deposits just beneath an 18,000-foot (5,500-meter) mountain called Mount Sharp. Scientists consider the sulfate-bearing unit to be a location rife with clues about how and why Mars morphed from a watery planet into the frozen place it is today, and researchers have long sought to explore the area in more depth. ...
... “Billions of years ago, waves on the surface of a shallow lake stirred up sediment at the lake bottom, over time creating rippled textures left in rock,” according to a NASA news release.
The wave-marked rocks were found about one-half mile (800 meters) into Curiosity’s ascent of Mount Sharp. As the rover climbed higher, it traveled over rocks that would have formed more recently. That’s why researchers didn’t expect to see such clear markers of a large body of water.
My son goes to Virginia Tech, and he thinks that his dad is a fossil ...New research reveals clues about the physical and chemical characteristics of Earth when life is thought to have emerged.
About four billion years ago, the first signs of life emerged on Earth in the form of microbes. Although scientists are still determining exactly when and how these microbes appeared, it’s clear that the emergence of life is intricately intertwined with the chemical and physical characteristics of early Earth. “It is reasonable to suspect that life could have started differently—or not at all—if the early chemical characteristics of our planet were different,” says Dustin Trail, an associate professor of earth and environmental sciences at the University of Rochester.
... Research into life and its origins typically involves a variety of disciplines including genomics, the study of genes and their functions; proteomics, the study of proteins; and an emerging field called metallomics, which explores the important role of metals in performing cellular functions. As life evolved, the need for certain metals changed, but Trail and McCollom wanted to determine what metals may have been available when microbes first appeared billions of years ago.
“When hypotheses are proposed for different origin-of-life scenarios, scientists have generally assumed all metals were available because there weren’t studies that provided geologically robust constraints on metal concentrations of fluids for the earliest times of Earth’s history,” Trail says.
... The researchers were surprised by what the model simulations indicated. Many origin-of-life researchers, for instance, consider copper a likely component in the chemistry that could have led to life. But Trail and McCollom did not find evidence that copper would have been abundant under the constraints in their analysis.
One metal they did test that may have been available in high concentrations was manganese. While it is rarely considered in origin-of-life scenarios, today manganese helps the body form bones and assists enzymes in breaking down carbohydrates and cholesterol. “Our research shows that metals like manganese may function as important links between the ‘solid’ Earth and emerging biological systems at Earth’s surface,” Trail says.
https://scitechdaily.com/new-models-...gins-on-earth/
A cosmic love triangle ...First “Unmistakable” Triassic-Era Caecilian Fossils Discovered, Revealing Origins of Living Amphibians
A team of Virginia Tech paleontologists, led by doctoral candidate Ben Kligman, have discovered the first Triassic-era caecilian fossils, the oldest-known of their kind, in Arizona. The find helps fill a massive gap of roughly 90 million years in the historical record of caecilians where no fossils had been previously found, baffling scientists. ... Named by Kligman as Funcusvermis gilmorei, the fossil extends the history of caecilians 35 million years back to Triassic Period, roughly 250 million to 200 million years ago. ... Prior to this new study, published today in the journal Nature, only 10 fossil caecilian occurrences were known, dating back to the Early Jurassic Period, about 183 million years ago. However, previous DNA studies estimated evolutionary origins of caecilians back to the Carboniferous or Permian eras, some 370 million to 270 million years ago, according to Kligman, marking that 87-million-year gap. However, no such fossils had been found. ...
Microscopic photograph of a lower jaw from Funcusvermis gilmorei soon after it was recovered during microscopic sorting of sediment from the Thunderstorm Ridge fossil site in the Petrified Forest National Park Paleontology Lab.
Gassho, JHubble Captures a Spectacular Triple Galactic Crash Course
A spectacular trio of merging galaxies in the constellation Boötes takes center stage in this stunning image from the Hubble Space Telescope. These three galaxies are set on a collision course and will eventually merge into a single larger galaxy, distorting one another’s spiral structure through mutual gravitational interaction in the process. An unrelated foreground galaxy appears to float serenely alongside the collision, and the smudged shapes of much more distant galaxies are visible in the background.
This colliding trio — known to astronomers as SDSSCGB 10189 — is a relatively rare combination of three large star-forming galaxies lying within only 50,000 light-years of one another. While that might sound like a safe distance, for galaxies this makes them extremely close neighbors! Our own galactic neighbors are much further away; Andromeda, the nearest large galaxy to the Milky Way, is more than 2.5 million light-years away from Earth. ...
stlahLeave a comment:
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This is so true, and no more true than in the sometime articles published on the positive health effects of meditation. I saw one today that I hesitated to put here, with a miniscule sample and poor study structure, supposedly showing that meditation has good effect on gut bacteria!
But, still, it is these science stories that should capture the world's daily news attention, not the belching of politicians or movie stars or balloons.
However, my real reason for putting stories here is not to comment on their worth for scientific advancement, but because the vast majority are stories ... about the ancient formation of stars and galaxies, about the balance of biology on this planet, within our cells and these amazing brains ... that should give us pause to consider what a wonder it is that we are here at all, alive, on this planet, in these bodies, in this universe.
Gassho, Jundo
stlahLast edited by Jundo; 02-14-2023, 01:42 AM.Leave a comment:
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You lose 2 dollars. I did 3 commands:
1- argue that chatgtp can’t practice medicine.
2. Add that chatgtp can assist doctors to 1.
3. Combine arguments 1. and 2.
[emoji3]
Gassho, JishinGTP, ST, LAHLeave a comment:
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As a Biomedical scientist I must say I really like this thread
Finally made it to the end, some good articles here. Though I would caution, as I think was mentioned by someone earlier, that for media releases on scientific discoveries, its like 90% 'hype'. Of course, people want to hear hope, and its good to inspire hope, but it can lead to exaggeration or over-simplification which can then get misrepresented by those not in the field.
Gassho,
Buyo (Steve)
Sat
Leave a comment:
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As a Biomedical scientist I must say I really like this thread Finally made it to the end, some good articles here. Though I would caution, as I think was mentioned by someone earlier, that for media releases on scientific discoveries, its like 90% 'hype'. Of course, people want to hear hope, and its good to inspire hope, but it can lead to exaggeration or over-simplification which can then get misrepresented by those not in the field.
Gassho,
Buyo (Steve)
SatLeave a comment:
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Hey there
Yeah I ran a bunch of medical or psychiatric conundrums through ChatGPT and it was knowledgable and the answers were surprisingly thoughtful, but fall way short of interepretative diagnositic processes. However, I thought it had some cool answers to questions like, "how do I become enlightened?" or "will the human species survive long-term?"
How much of our decision making will we eventually devolve to AI? I tell you, New Zealand could do with AI-nurse-bot's, not to replace humans, but to complement them as the nursing workforce continues to contract locally and globally.
Gassho, Tokan
satlahLeave a comment:
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While ChatGPT has been trained on a large corpus of text, including medical information, it is important to note that it is not capable of practicing medicine independently. The ability to pass a medical exam is not the same as having the training, skills, and experience necessary to diagnose and treat patients.
However, AI like ChatGPT can serve as a valuable tool in assisting medical professionals in providing better care for their patients. By providing access to vast amounts of information and data, AI can help doctors make more informed decisions and provide more effective treatment plans. Additionally, AI can assist in streamlining administrative tasks, freeing up more time for medical professionals to focus on patient care.
There are several reasons why ChatGPT cannot practice medicine independently. First, it lacks the hands-on experience necessary to diagnose and treat patients. Medicine is a hands-on field that requires direct interaction with patients, examination of symptoms, and the ability to perform procedures. ChatGPT does not have a physical body and cannot perform these tasks.
Second, medicine is a constantly evolving field, and it is important for medical professionals to stay up to date with the latest developments and best practices. ChatGPT is not capable of continuing to learn and grow in the same way that a human medical professional would.
Finally, medical professionals must consider the ethical and legal implications of their actions. They must make decisions based on the best interests of their patients, and must adhere to strict codes of conduct and standards of care. ChatGPT does not have the ability to understand and act in accordance with these ethical and legal considerations.
While ChatGPT may have knowledge about medical topics, it is not capable of practicing medicine independently. However, AI has the potential to serve as a valuable tool in assisting medical professionals in providing better care for their patients. The field of medicine requires hands-on experience, ongoing learning and development, and ethical and legal considerations that ChatGPT is not capable of handling.
My 2 cents,
Gassho, Jishin, ST, LAHLeave a comment:
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