The Zen of Technology & Scientific Discovery! (& Robots)

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  • Jundo
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    Big discovery in those recovered asteroid samples ...

    Building Blocks of Life? NASA Reveals 4.5-Billion-Year-Old Asteroid Bennu Sample

    Initial studies of the 4.5-billion-year-old asteroid Bennu sample collected in space and brought to Earth by NASA show evidence of high-carbon content and water, which together could indicate the building blocks of life on Earth may be found in the rock.

    BELOW: A view of the outside of the OSIRIS-REx sample collector. Sample material from asteroid Bennu can be seen on the middle right.


    https://scitechdaily.com/building-bl...-bennu-sample/
    Diamond Sutra ...

    So you should view this fleeting world --
    A star at dawn, a bubble in a stream ...

    Supernova Bubble Captured in Hubble Time-Lapse Movie – 20,000-Year-Old Explosion Still Expanding at 500,000 MPH

    A blink between Hubble images taken in 2001 (with Wide Field Planetary Camera 2 (WFPC2)) and 2020 (with Wide Field Camera 3 (WFC3)) shows gossamer filaments of glowing hydrogen in orange and cooling ionized oxygen in blue. The hydrogen filaments resemble lines in a wrinkled bedsheet seen from the side. The wrinkles arise as the shock wave encounters more or less dense material in the interstellar medium. Analyzing the shock wave’s location, astronomers found that the filaments have not slowed down at all in the last 20 years of Hubble observations, and they haven’t changed shape. The material is speeding into interstellar space at over half a million miles per hour—fast enough to travel from Earth to the Moon in less than half an hour. The shock wave is moving toward the top of these images.


    https://scitechdaily.com/supernova-b...at-500000-mph/
    I like Gaga in 'A Star is Born' more than Streisand, but the classic is Judy Garland ...

    NASA’s Webb Reveals Breathtaking Glimpse of Star Birth in Ethereal Depths

    This video compares images of star-forming region NGC 346 taken in visible light with the Hubble Space Telescope’s ACS instrument, near-infrared with the James Webb Space Telescope’s NIRCam instrument, and mid-infrared with Webb’s MIRI instrument. Hubble’s visible-light image is filled with thousands of stars, as well as curtains of hydrogen and oxygen gas colored blue. In Webb’s near-infrared image, pink represents energized hydrogen, while orange represents dense, molecular hydrogen. Webb’s mid-infrared image highlights bright patches of star formation, diffuse pink emission from warm dust, and blue filaments of dusty and sooty material. ... The field of view shown in this image is approximately 150 light-years across. ...


    https://scitechdaily.com/nasas-webb-...hereal-depths/
    A speedy subaru ...

    Revolutionary “New Lens” Into the Universe’s Most Energetic Particles

    Scientists from Osaka Metropolitan University have harnessed the Subaru Telescope to observe cosmic-ray showers with unprecedented clarity. This new method could lead to profound discoveries about the Universe, including insights into dark matter. ...

    ... When a high-energy cosmic ray collides with the Earth’s atmosphere, it generates an enormous number of particles known as an extensive air shower. ...

    BELOW: An example of a cosmic-ray extensive air shower recorded by the Subaru Telescope. The highlighted tracks, which are mostly aligned in similar directions, show the shower particles induced from a high-energy cosmic ray.

    https://scitechdaily.com/revolutiona...tic-particles/
    From vast space to smallest time ...

    Understanding Attoseconds: The Tiny Time Scale Behind Nobel Prize-Winning Research

    The 2023 Nobel Prize in physics recognized three researchers for their work with attosecond light pulses, revolutionizing the study of rapid electron movements and broadening understanding in various fields of physics and chemistry.

    “Atto” is the scientific notation prefix that represents 10-18, which is a decimal point followed by 17 zeroes and a 1. So a flash of light lasting an attosecond, or 0.000000000000000001 of a second, is an extremely short pulse of light.

    In fact, there are approximately as many attoseconds in one second as there are seconds in the age of the universe.

    https://scitechdaily.com/understandi...ning-research/
    So very slow, compared to an attosecond ...

    One-Millionth of One-Millionth of a Second – Scientists View the “Transition State” of a Photochemical Reaction in Real-Time

    Scientists used ultrafast electron diffraction to image the structure of the pericyclic minimum, the “transition state” of electrocyclic reactions.

    In chemical reactions, molecules proceed during their transformation from reactants into reaction products through a critical geometry. In chemistry, geometry refers to the arrangement of atoms in a molecule. Scientists often call critical geometry in reactions a transition state. This state has an almost incomprehensibly short lifetime of less than one-millionth of one-millionth of a second.

    BELOW: Artist’s illustration of the observed photochemical “transition state” structure (center).


    https://scitechdaily.com/one-million...-in-real-time/
    Lost plate found ...

    Surprising Tectonic Discovery: Geologist Unexpectedly Finds Remnants of a Lost Mega-Plate

    A geologist has successfully reconstructed a previously unknown tectonic plate named Pontus, once approximately one-fourth the size of the Pacific Ocean. This discovery was made through field research in various regions, including Japan, Borneo, and the Philippines.

    Some amazing medical stories ...

    It is said that this little girl will be largely fine, leading a very normal life ...

    Doctors disconnect half of SoCal 6-year-old's brain

    A 6-year-old girl with a rare neurological disease recently underwent life-saving surgery that disconnected half of her brain.



    ALSO:

    A monkey pig or a pig monkey ... a ponkey kidney ...

    Gene-edited pig kidney keeps monkey alive for 2 years, trial finds, a step toward longer-lasting human transplants

    The scientists genetically modified the pigs so their kidneys could be transferred to another species and to improve the chances that the organs wouldn’t be rejected. Even when a human donates an organ to another human, the recipient has to take drugs to suppress their immune system for the rest of their lives so their body does not reject the donor organ.

    With previous pig-to-primate donation experiments, even those involving genetically modified pigs, scientists had to use a significant number of immunosuppressant drugs, meaning the experiments would not be translatable to a human organ donation experiment, researchers said. But with this trial, the genetic modifications were effective enough that they needed only about as much medicine as a human could tolerate.

    The team transplanted pig kidneys into more than 20 monkeys, although not all of the pigs had all of the gene edits.

    None of the monkeys that got kidneys from the pigs without the seven human genes survived more than 50 days. The monkeys that got the full combination lived a lot longer: Five lived for more than a year, and one lived for more than two. Tests showed that the single donated kidney seemed to perform as well as two natural kidneys.

    About 13 people die every day while waiting for a kidney transplant because of a lack of organ donors, but some scientists think pigs could be the answer. In a new trial that researchers say is the largest of its kind, researchers transplanted kidneys from genetically modified pigs into monkeys that lived for what’s considered a record amount of time.
    Problems for AI to solve ...

    Shaking Up Predictions: Deep Learning Revolutionizes Earthquake Forecasts

    Scientists have developed a deep learning model, RECAST, to forecast earthquake aftershocks. This model demonstrates superior adaptability and scalability compared to the existing ETAS model, especially with larger seismological datasets. The model could lead to improved forecasts, even in areas with limited data, by leveraging information from multiple global regions.

    https://scitechdaily.com/shaking-up-...ake-forecasts/
    EVEscape: The AI Revolution in Forecasting Viral Variants Before They Emerge

    New AI tool called EVEscape uses evolutionary and biological information to predict how a virus could change to escape the immune system. The tool successfully predicted the most concerning new variants that occurred during the COVID-19 pandemic. Researchers say the tool can help inform the development of vaccines and therapies for SARS-CoV-2 and other rapidly mutating viruses.

    https://scitechdaily.com/evescape-th...e-they-emerge/
    New proteins, better batteries: Scientists are using AI to speed up discoveries

    On Thursday, the U.S. National Academies convened a two-day meeting on the potential for AI to change science. "AI scientists can really be more systematic, more comprehensive and not make errors," says Yolanda Gil, director of AI and data science initiatives at the Information Sciences Institute at the University of Southern California, who is attending the event.

    Rather than using AI to do all science, she envisions a future in which AI systems plan and execute experiments, in collaboration with their human counterparts. In a world facing increasingly complex technical challenges, "there's not enough humans to do all this work," she says.

    https://www.npr.org/sections/health-...ns-drugs-solar
    AI-Powered Lasers: A Modern Solution to Space Debris

    Hang Woon Lee, director of the Space Systems Operations Research Laboratory at WVU, said a junkyard of human-made debris, including defunct satellites, is accumulating around Earth. The more debris in orbit, the higher the risk that some of that debris will collide with manned and unmanned space assets. He said he believes the best chance for preventing those collisions is an array of multiple lasers mounted to platforms in space. The artificial intelligence-powered lasers could maneuver and work together to respond rapidly to debris of any size.


    https://scitechdaily.com/ai-powered-...-space-debris/
    Some AI problems ...

    Jevons’ Paradox: AI Could Use As Much Electricity As Entire Countries

    Generative AI models, like OpenAI’s ChatGPT, consume large amounts of energy during training and operational use. While global efforts are underway to improve AI’s energy efficiency, the increased efficiency might inadvertently boost demand due to Jevons’ Paradox. Given current projections, AI’s electricity consumption could rival that of entire nations by 2027. The researchers stress the importance of mindful AI application due to its energy-intensive nature. ...

    https://scitechdaily.com/jevons-para...ire-countries/
    Some AI problems solved ...

    AI Game-Changer: Nanoelectronic Devices Uses 100x Less Energy

    Northwestern University’s new nanoelectronic device offers energy-efficient, real-time AI tasks without relying on the cloud. Ideal for wearables, it processes data instantly and diagnosed heart conditions with 95% accuracy in tests. This innovation promises faster, efficient, and private health monitoring.

    ... With its tiny footprint, ultra-low power consumption, and lack of lag time to receive analyses, the device is ideal for direct incorporation into wearable electronics (like smartwatches and fitness trackers) for real-time data processing and near-instant diagnostics.

    “Today, most sensors collect data and then send it to the cloud, where the analysis occurs on energy-hungry servers before the results are finally sent back to the user,” said Northwestern’s Mark C. Hersam, the study’s senior author. “This approach is incredibly expensive, consumes significant energy and adds a time delay. Our device is so energy efficient that it can be deployed directly in wearable electronics for real-time detection and data processing, enabling more rapid intervention for health emergencies.”

    https://scitechdaily.com/ai-game-cha...x-less-energy/
    Empathizing with empathetic AI ...

    AI Empathy: Is It Technology or Just Our Perceptions?

    Study shows users can be primed to believe certain things about an AI chatbot’s motives, which influences their interactions with the chatbot. ... Researchers from MIT and Arizona State University found that priming users — by telling them that a conversational AI agent for mental health support was either empathetic, neutral, or manipulative — influenced their perception of the chatbot and shaped how they communicated with it, even though they were speaking to the exact same chatbot. ... Most users who were told the AI agent was caring believed that it was, and they also gave it higher performance ratings than those who believed it was manipulative. At the same time, less than half of the users who were told the agent had manipulative motives thought the chatbot was actually malicious, indicating that people may try to “see the good” in AI the same way they do in their fellow humans.


    crAIvings ...

    Emotional Bytes: Can AI Crave a Favorite Food?

    Penn State researchers are developing an electronic tongue that simulates the human process of gustation, which could influence AI to make decisions more like humans. This innovation is part of an effort to incorporate the emotional intelligence aspect, often overlooked in AI research. This electronic gustatory system can currently detect all five primary tastes and has numerous potential applications, from AI-driven diets to personalized restaurant offerings. ... Electronic tongue’ holds promise as possible first step to artificial emotional intelligence.

    https://scitechdaily.com/emotional-b...favorite-food/
    AI has feelings ... but trees don't ...

    Scientists Debunk the Myth: Do Trees Really Have Feelings?

    Researchers scrutinized claims made in two popular books about trees having human-like traits and emotions. Published in Trends in Plant Science, their findings challenge many of these claims as unscientific. They caution against anthropomorphizing plants and highlight issues like the flawed “mother tree concept” and the dangers of making decisions based on appealing but inaccurate narratives, especially in the context of climate change adaptation.

    ... The researchers report that in those works, trees are attributed with human characteristics and behaviors, including the ability to feel pain and pleasure, to communicate with one another, and to act altruistically. ...

    ... Finally, the authors point out the fatal consequences such claims could have for the adaptation of forests to climate change if political decisions are “based on pleasant-sounding but false messages” rather than scientific fact, adds Robinson. ...



    https://scitechdaily.com/scientists-...have-feelings/
    I don't know how practical this really is, but I want one!

    See Japanese 'ARCHAX' robot with $3 million price tag

    I want one of these too ...

    The blimp is back – and this time, it’s tiny

    South African startup Cloudline has received millions of dollars in investment for its mini blimps. Just over 18 meters (60 feet) long and with a miniscule net weight of two to three kilograms (around four to seven pounds), the company is pitching them as an alternative to helicopters and other vertical take-off and landing aircraft, and with payload capacities outstripping those of drones.

    Cloudline has already received approval from local authorities to begin flying its airships in South Africa and is in talks with partners in Namibia, Mozambique and Kenya to begin operations, says CEO Spencer Horne.

    The helium-filled blimps are fitted with solar panels and backup batteries to power their engines, have a flight time of up to 12 hours and a range of up to 400 kilometers (249 miles), flying at a height up to 1,220 meters (4,000 feet) above take-off level.

    Flight is fully autonomous, with each blimp following predetermined waypoints. In the event an airship encounters an abnormality, it will reroute to a predetermined point and wait for instruction from a human, who has access to its telemetry data.

    Startup Cloudline is dreaming small with a fleet of mini autonomous airships. Could the idea take off?


    Genetics surprises ...

    Divergent DNA: The Accidental Discovery That’s Shaking Genetics

    Researchers found an unexpected genetic variation in a new protist species, challenging established understanding of DNA-to-protein translation and emphasizing the mysteries that nature still holds. ...

    https://scitechdaily.com/divergent-d...king-genetics/
    Why fix what ain't broken?

    Darwin’s Dilemma: “Paradox of Stasis” Lizard Study Challenges the Rules of Evolutionary Biology

    By lassoing lizards, putting tiny chips on their legs, and tracking them for three years, Georgia Tech’s James Stroud revealed why species often appear unchanged for millions of years despite Charles Darwin’s theory of constant evolution. ...

    To his surprise, Stroud found that the stabilizing form of natural selection — that which maintains a species’ same, average features — was extremely rare. In fact, natural selection varied massively through time. Some years, lizards with longer legs would survive better, and other years, lizards with shorter legs fared better. For other times, there was no clear pattern at all. “The most fascinating result is that natural selection was extremely variable through time,” Stroud said. “We often saw that selection would completely flip in direction from one year to the next. When combined into a long-term pattern, however, all this variation effectively canceled itself out: Species remained remarkably similar across the entire time period.”

    https://scitechdaily.com/darwins-dil...onary-biology/
    People even lost their shoes back then ...

    'Prehistoric footwear' was discovered in Spanish cave by miners, scientists reveal in new study
    Some 20 pairs of sandals are said to be at least 6,200 years old


    What may have been the oldest pair of shoes in Europe were discovered in a cave in Spain and are now thought to be much older than scientists previously thought.

    About 20 pairs of the sandals are at least 6,200 years old — and possibly older — while other woven objects in the cave are dated back 9,500 years, according to a new study by scientists. The shoes measured around 20.5cm — or a little over 8 inches.

    The news emerged after scientists used carbon-dating on 76 objects from the Cueva de los Murciélagos, Albuñol, near Granada, that had been dug out by miners in the 19th century.


    https://www.foxnews.com/lifestyle/pr...entists-reveal
    Mr. Musk could fall on your head ...

    SpaceX fires back at FAA report suggesting its Starlink internet constellation could be deadly

    The 35-page analysis, compiled in part by the nonprofit research group The Aerospace Corporation, offers a dire picture of the potential dangers associated with large networks of satellites such as Starlink, suggesting that by 2035, “if the expected large constellation growth is realized and debris from Starlink satellites survive reentry … one person on the planet would be expected to be injured or killed every two years.”

    It also estimates that the probability of an aircraft being downed by a collision with falling space debris could be 0.0007 per year by 2035.



    https://us.cnn.com/2023/10/10/world/...scn/index.html
    Gassho, J

    satLAH

    Leave a comment:


  • Jundo
    replied
    FROM SCI-FI TO REALITY: DOES A BRAIN IN A DISH HAVE MORAL RIGHTS?

    Inventors of brain-cell-based computers collaborate with a global team of ethicists to examine the ethical applications of bio-computing.

    Bio-computing, once a concept confined to science fiction, is now a reality. As such, it’s crucial to begin contemplating its ethical research and application, according to a global assembly of specialists.

    The creators of DishBrain have collaborated with bioethicists and medical scientists to outline a comprehensive framework. Their insights and recommendations on addressing this emerging field can be found in a recently published article in Biotechnology Advances.

    “Combining biological neural systems with silicon substrates to produce intelligence-like behavior has significant promise, but we need to proceed with the bigger picture in mind to ensure sustainable progress,” says lead author Dr. Brett Kagan, Chief Scientific Officer of biotech start-up Cortical Lab. The group was made famous by their development of DishBrain – a collection of 800,000 living brain cells in a dish that learned to play Pong.

    ...

    The researchers point out that it is worth working through these moral issues, as the potential impact of bio-computing is significant.
    “Silicon-based computing is massively energy-hungry with a supercomputer consuming millions of watts of energy. By contrast, the human brain uses as little as 20 watts of energy – biological intelligences will show similar energy efficiency,” says Dr Kagan.

    “As it stands, the IT industry is a massive contributor to carbon emissions. If even a relatively small number of processing tasks could be done with bio-computers, there is a compelling environmental reason to explore these alternatives.”



    Gassho, J

    stlah

    Leave a comment:


  • Jundo
    replied
    Discoveries and JUMBO mysteries up there ...

    Unprecedented discovery seems to defy fundamental astronomical theories

    The Orion Nebula, a glowing cloud of dust and gas, is one of the brightest nebulae in the night sky and identifiable as the sword in the Orion constellation. Located 1,300 light-years from Earth, the nebula has long presented astronomers with a wealth of celestial objects to study, including planet-forming disks around young stars and brown dwarfs, or objects with a mass between that of planets and stars.
    [Astonomers using Webb] zoomed in on the Trapezium Cluster, a young star-forming region that’s about 1 million years old, filled to the brim with thousands of new stars. In addition to the stars, the scientists spotted brown dwarfs, which are too small to kick-start the nuclear fusion at their cores to become stars.

    On the hunt for other low-mass isolated objects, the astronomers found something they had never seen: pairs of planet-like objects with masses between 0.6 and 13 times the mass of Jupiter that appear to defy some fundamental astronomical theories ... The astronomers found 40 pairs of JuMBOs and two triple systems, all on wide orbits around one another. Although they exist in pairs, the objects are typically about 200 astronomical units apart, or 200 times the distance between Earth and the sun. It can take between 20,000 and 80,000 years for the objects to complete an orbit around each other.

    ... But no existing theories explain how the JuMBOs formed, or why they’re present in the Orion Nebula ... For instance, some may consider the JuMBOs to be like rogue planets, or objects of planetary mass that freely travel through space without orbiting stars. But many rogue planets begin by orbiting stars before being ejected, and it would be hard to explain how pairs of them were kicked out at the same time while remaining gravitationally connected to each other. ... Pearson said. “The main thing that we learn from this is that there is something fundamentally wrong with either our understanding of planet formation, star formation, or both.”

    BELOW: Five JuMBOs can be seen in this image, which zoomed in on the finer details of the larger Webb portrait of the Trapezium Cluster in the Orion Nebula.

    Astronomers find unexpected pairs of unusual planet-like objects in the Orion Nebula using the James Webb Space Telescope.
    Explosive mysteries ...

    Hubble’s Hitchcock Moment: A Bizarre Explosion in Unexpected Place

    A clear starry night is deceptively tranquil to backyard skygazers. In reality, the sky is ablaze with things that go pop in the night – like paparazzi flash cameras going off. Most of these flashes are stellar explosions or collisions. They are so faint they can only be captured by the unblinking eye of telescopes that continually keep watch on the nighttime sky for such transients.

    Among the rarest of these random cosmic events are a small class called Luminous Fast Blue Optical Transients (LFBOTs). They shine intensely in blue light and evolve rapidly, reaching peak brightness and fading again in a matter of days, unlike supernovae which take weeks or months to dim.

    The first LFBOT was found in 2018. Presently, they are captured once a year and so only a handful are known. There are several theories behind what causes the powerful explosions. But Hubble came along and made this phenomenon even more mysterious.

    One LFBOT popped up in 2023 in a place where no one expected it be – far between two galaxies. Only Hubble could exactly pinpoint its surprising location. If a flavor of extraordinarily powerful supernovae causes LFBOTs, they should blow up in the spiral arms of galaxies where star birth is underway. The massive newborn stars behind supernovae don’t live long enough to go wandering off beyond their nesting ground inside a galaxy.

    BELOW: A Hubble Space Telescope image of a Luminous Fast Blue Optical Transient (LFBOT) designated AT2023fhn, indicated by pointers. ... The surprise is that this latest transient, seen in 2023, lies at a large offset from both the barred spiral galaxy at right and the dwarf galaxy to the upper left.


    https://scitechdaily.com/hubbles-hit...xpected-place/
    A Billion-Year-Old “Circumnuclear Ring ...

    Hubble Captures Galaxy With Brilliant Blue Arms and Billion-Year-Old “Circumnuclear Ring”

    NASA’s Hubble Space Telescope has captured this detailed image of NGC 6951 ... an intermediate spiral galaxy 78 million light-years away in the Cepheus constellation. ... Turbulent regions of gas, shown in dark red, surround the bright blue pinpricks that are star clusters. ... At the center of NGC 6951 lies a supermassive black hole surrounded by a ring of stars, gas, and dust about 3,700 light-years across. This “circumnuclear ring” is between 1 and 1.5 billion years old and has been forming stars for most of that time. Scientists hypothesize that interstellar gas flows through the dense, starry bar of the galaxy to the circumnuclear ring, which supplies new material for star formation. Up to 40 percent of the mass in the ring comes from relatively new stars that are less than 100 million years old. Spiral lanes of dust, shown in dark orange, connect the center of the galaxy to its outer regions, contributing more material for future star formation. ...


    https://scitechdaily.com/hubble-capt...mnuclear-ring/
    Psyched up about psyche ...

    For the first time, a NASA mission is setting off on a distant journey to visit a metal world in our solar system.

    Getting up close with the asteroid known as Psyche is the only way to determine whether it’s the rare exposed core of an early planetary building block, according to scientists. The metal-rich asteroid is in the main asteroid belt between the orbits of Mars and Jupiter. The namesake Psyche spacecraft is expected to lift off Thursday. ... The giant space rock is about 235 million to 309 million miles (378 million to 497 million kilometers) from the sun. After launch, the mission will arrive in orbit around the asteroid in 2029 and spend about two years studying Psyche with a suite of scientific instruments to determine its true nature. ... Scientists believe that studying Psyche could help them address key questions about planet formation. Earth, Mercury and Mars have metallic cores, but they are too deep below their planets’ rocky shells to be seen or studied directly. ...

    Artist's conception below:


    https://us.cnn.com/2023/10/06/world/...scn/index.html
    Mysteries remaining inside us ... liking physics and biology ...

    Challenging Long-Held Assumptions: New Research Reveals How Nuclear Spin Impacts Biological Processes

    Researchers discovered the significant impact of nuclear spin on biological processes, specifically oxygen dynamics in chiral environments [Chirality, or handedness, means that an object or molecule cannot be superimposed on its mirror image by any translations or rotations]. This breakthrough could revolutionize biotechnology, quantum biology, isotope separation, and NMR technology. ... Scientists have long believed that nuclear spin had no impact on biological processes. However, recent research has shown that certain isotopes behave differently due to their nuclear spin. ... This connection between the tiny world of particles and living beings likely goes back billions of years when life began and molecules with a special shape called chirality appeared. Chirality is important because only molecules with the right shape can do the jobs they need to in living things. ...

    https://scitechdaily.com/challenging...cal-processes/
    Parts of us get overlooked ...

    Princeton Scientists Discover Overlooked Parts of Proteins That Are Critical to Fundamental Functions of Life

    Protein condensates (shown here in a microscope image) are critical to the process of gene expression in cells, and condensate formation depends on proteins’ intrinsically disordered regions. ...

    According to textbooks, proteins work by folding into stable 3D shapes that, like Lego blocks, precisely fit with other biomolecules. However, this depiction of proteins, the “workhorses of biology,” doesn’t tell the whole story. Around half of all proteins have stringy, unstructured bits hanging off them, dubbed intrinsically disordered regions, or IDRs. Now, a multi-institutional collaboration has uncovered how a key aspect of cell biology is controlled by IDRs. Their study, recently published in the journal Cell, reveals that IDRs have specific and important interactions that play a central role in chromatin regulation and gene expression, essential processes across every living cell. ... The researchers focused on disordered regions of the human cBAF complex, a multi-component group of proteins in the nucleus that works to open up the densely coiled-up DNA inside cells called chromatin, enabling genes along DNA to be expressed and turned into proteins. ... In particular, the study revealed that the IDRs form little droplets called condensates that separate out from surrounding cellular fluid, just like drops of oil in water. The specific interactions that happen in these condensates allow proteins and other biomolecules to congregate in particular locations to carry out cellular activities. ...



    Who discovered America?

    Scientists say they’ve confirmed evidence that humans arrived in the Americas far earlier than previously thought

    When the discovery of fossilized footprints made in what’s now New Mexico was made public in 2021, it was a bombshell moment for archaeology, seemingly rewriting a chapter of the human story. Now new research is offering further evidence of their significance. While they look like they could have been made yesterday, the footprints were pressed into mud 21,000 to 23,000 years ago, according to radiocarbon dating of the seeds of an aquatic plant that were preserved above and below the fossils.

    This date dramatically pushed back the timeline of humans’ history in the Americas, the last landmass to be settled by prehistoric people. The 61 dated prints, which were discovered in the Tularosa Basin, near the edge of an ancient lake in White Sands National Park, were made ... around the time of the Last Glacial Maximum, a period between 19,000 and 26,000 years ago when two massive ice sheets covered the northern third of North America, reaching as far south as New York City, Cincinnati and Des Moines, Iowa. The ice and cold temperatures would have made a journey between Asia and Alaska impossible during that time, meaning the people who made the footprints likely arrived much earlier.

    Speaking of climate changes ... maybe some good news ... but still seems like a drop in the bucket ...

    U.S. transition to clean energy is happening faster than you think, reporter says

    Recently, a team of reporters at the New York Times produced what kind of feels like an optimistic break from the doom and gloom of climate news. Huge swaths of our country are turning away from fossil fuels as an energy source and investing in wind, solar and other renewable energy. We're talking places like Texas and Oklahoma, once dominated by oil and gas, now building essentially new industries. The New York Times' three-part series called "The Energy Transition" explores the speed, challenges, politics and economics of this move toward newer sources of energy.

    https://www.npr.org/2023/10/05/12038...-reporter-says
    ... and then there is climate ignorance ...

    People working on climate solutions are facing a big obstacle: conspiracy theories

    Climate disinformation in the past — sometimes paid for by fossil fuel interests — often related to false ideas that global warming is a scam or that the threat is overblown. Those falsehoods are still around, but what we're seeing a lot more of these days are attacks on climate solutions even if we don't always know who funds them. Think attacks on renewables. False ideas that wind turbines cause cancer or cause birth defects in animals. Disinformation may be spreading because solutions are really spreading.

    For instance, this weekend we'll have a story about a trend in urban planning called 15-minute cities — designing cities so that you access amenities in a short walk, bike ride or trip on public transport. Now there's a conspiracy theory saying that this is a way to restrict people's movement or to trap people in an open-air prison. ...

    ... Different kinds of false information spread in different ways. But if you're considering misleading claims about climate — that's predominantly on the right. And that involves an information ecosphere defined by Joe Rogan, as we heard above, but also Alex Jones, Breitbart, the Daily Wire, the Daily Mail, the New York Post, and above all Fox News. ...

    https://www.npr.org/2023/10/05/12038...disinformation
    AI may be an improvement over human idiocy ... The billionaire guy who makes my Japanese smart phone says ...

    SoftBank CEO says artificial general intelligence will come within 10 years

    SoftBank CEO Masayoshi Son said he believes artificial general intelligence (AGI), artificial intelligence that surpasses human intelligence in almost all areas, will be realized within 10 years.

    Speaking at the SoftBank World corporate conference, Son said he believes AGI will be ten times more intelligent than the sum total of all human intelligence. He noted the rapid progress in generative AI that he said has already exceeded human intelligence in certain areas.

    “It is wrong to say that AI cannot be smarter than humans as it is created by humans,” he said. “AI is now self learning, self training, and self inferencing, just like human beings.”

    Son has spoken of the potential of AGI — typically using the term “singularity” — to transform business and society for some years, but this is the first time he has given a timeline for its development.

    He also introduced the idea of “Artificial Super Intelligence” at the conference which he claimed would be realized in 20 years and would surpass human intelligence by a factor of 10,000.

    Son is known for several canny bets that have turned SoftBank into a tech investment giant as well as some bets that have spectacularly flopped.

    He’s also prone to making strident claims about the transformative impact of new technologies. His predictions about the mobile internet have been largely borne out while those about the Internet of Things have not [JUNDO: Yet! ].

    https://us.cnn.com/2023/10/04/tech/j...ntl/index.html
    Crispr gets Crispier ...

    Gene-Editing Breakthrough: Compact Enzyme Promises More Effective Treatments

    A new CRISPR gene-editing tool, AsCas12f, smaller than the commonly used Cas9, has been engineered for better efficiency and effectiveness in treating genetic disorders. Tested successfully in mice, this tool could lead to more compact and efficient genome-editing applications in humans. ... The compact size means that more of it can be packed into carrier viruses and delivered into living cells, making it more efficient.

    Researchers created a library of possible AsCas12f mutations and then combined selected ones to engineer an AsCas12f enzyme with 10 times more editing ability than the original unmutated type.


    Gassho, J

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  • Jundo
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    Speaking of black holes ... space sounds! ...

    Echoes Across Space: The Universal Sound of Black Holes

    ... Scientists at HITS, Germany, have predicted that the ‘chirp’ noise generated when two black holes merge preferentially occurs in two universal frequency ranges. ... The merger of two stellar-mass black holes releases gravitational waves with escalating frequency, known as the chirp signal, which can be detected on Earth. By analyzing the progression of this frequency (the chirp), scientists can calculate the “chirp mass,” a mathematical representation of the combined mass of the two black holes.



    Attaboy for the attosecond ...

    Nobel Prize in physics won by trio who created rapid flashes of light to ‘capture the shortest of moments’

    The 2023 Nobel Prize in physics has been awarded to a team of scientists who created a ground-breaking technique using lasers to understand the extremely rapid movements of electrons, which were previously thought impossible to follow.

    Pierre Agostini, Ferenc Krausz and Anne L’Huillier “demonstrated a way to create extremely short pulses of light that can be used to measure the rapid processes in which electrons move or change energy,” the Nobel committee said when the prize was announced in Stockholm on Tuesday. ... The movements of electrons inside atoms and molecules are so rapid that they are measured in attoseconds – an almost incomprehensibly short unit of time. “An attosecond is to one second as one second is to the age of the universe,” the committee explained. ... “This is another transformative moment in physics and in science, where a whole new (way) to probe the universe was opened up by the work of these three physicists,” Moloney added.


    The 2023 Nobel Prize in physics has been awarded to a team of scientists who created a ground-breaking technique using lasers to understand the extremely rapid movements of electrons, which were previously thought impossible to follow.

    So extreme ... like on other worlds ...

    Surviving the Extremes: Exploring the Existence of Life at 52°C/124°F

    Biologists from Syracuse University are examining the processes that enable microbial eukaryotes to flourish in the harsh environment of ... some of the harshest environments on Earth: extremely hot and acidic geothermal lakes. ... Oliverio notes that the team’s genome-scale findings will contribute important missing data into reconstructions of the tree of life. “This will further our understanding of the distribution and evolution of life on Earth.” ...

    https://scitechdaily.com/surviving-t...f-life-at-125/
    Where life came from?

    From Atoms to Organisms: “Assembly Theory” Unifies Physics and Biology To Explain Evolution and Complexity

    Assembly theory bridges the gap between physics and biology in explaining how complex objects are identifiable as products of evolution and how reusability of parts allows novelty and identical intricate items to be constructed by selection in nature ... “Assembly Theory provides a completely new lens for looking at physics, chemistry, and biology as different perspectives of the same underlying reality,” explained lead author Professor Sara Walker, a theoretical physicist and origin of life researcher from Arizona State University. “With this theory, we can start to close the gap between reductionist physics and Darwinian evolution – it’s a major step toward a fundamental theory unifying inert and living matter.” ...

    https://scitechdaily.com/from-atoms-...nd-complexity/
    Conscious nonsense? ... panpsychic panning ...

    Consciousness & Controversy: Why Leading Theory Faces “Pseudoscience” Backlash

    Tensions are high in consciousness research, with over 100 researchers criticizing the Integrated Information Theory (IIT) as pseudoscientific. While IIT suggests that consciousness is more widespread than traditionally believed, critics argue that its broad claims lack comprehensive empirical support. ...

    Integrated information theory – often referred to as IIT – is a very ambitious theory of consciousness proposed by neuroscientist Giulio Tononi. It ultimately aims to give mathematically precise conditions for when any system – a brain or some other lump or matter – is or is not conscious. The theory revolves around a mathematical measure of integration of information, or interconnections, labeled with the Greek letter ϕ. The basic idea is that a system becomes conscious at the precise moment when there is more ϕ in the system as a whole than in any of its parts. IIT implies that many more things are conscious than we ordinarily suppose. This means it gets close to a kind of “panpsychism” – the view that consciousness pervades the physical universe. Having said that, there are big differences between IIT and the new wave of Bertrand Russell-inspired panpsychism which has recently been making waves in academic philosophy, and which has been the focus of much of my research. IIT even implies, as pointed out by the computer scientist Scott Aaronson, that an inactive grid of connected logic gates would be conscious.

    https://scitechdaily.com/consciousne...ence-backlash/
    A practical invention that will save lives ...

    MIT’s New Desalination System Produces Freshwater That Is “Cheaper Than Tap Water”

    Engineers at MIT and in China are aiming to turn seawater into drinking water with a completely passive device that is inspired by the ocean, and powered by the sun. ... The configuration of the device allows water to circulate in swirling eddies, in a manner similar to the much larger “thermohaline” circulation of the ocean. This circulation, combined with the sun’s heat, drives water to evaporate, leaving salt behind. The resulting water vapor can then be condensed and collected as pure, drinkable water. In the meantime, the leftover salt continues to circulate through and out of the device, rather than accumulating and clogging the system. ... The researchers estimate that if the system is scaled up to the size of a small suitcase, it could produce about 4 to 6 liters of drinking water per hour and last several years before requiring replacement parts. At this scale and performance, the system could produce drinking water at a rate and price that is cheaper than tap water.

    “For the first time, it is possible for water, produced by sunlight, to be even cheaper than tap water,” says Lenan Zhang, a research scientist in MIT’s Device Research Laboratory. The team envisions a scaled-up device could passively produce enough drinking water to meet the daily requirements of a small family. The system could also supply off-grid, coastal communities where seawater is easily accessible.


    https://scitechdaily.com/mits-new-de...han-tap-water/
    A bunch of AI issues ...

    AI girlfriends imperil generation of young men

    Using Artificial Intelligence apps, "young men get in these AI relationships," says Professor Liberty Vittert. "And because the AI learns from you exactly what you like and don't like, you end up having these perfect relationships. So when you go into real life...there's ups and downs they are not able to deal with."


    https://us.cnn.com/videos/business/2...ion-of-men.cnn
    Pop idols who don't need to be paid ...

    ‘The only thing we can’t do is sign autographs’: The rise of virtual K-pop bands

    Built using AI technology, Eternity is one of the latest South Korean acts pushing the boundary between real and virtual entertainment. And the group’s creator and management company, Pulse9, believes that computer-generated stars have a significant edge over their real-life counterparts.

    As with most popular K-pop groups, Eternity’s members include a group leader, vocalists, rappers and dancers. But one member in particular, Zae-in, can do it all. “Zae-in has (a combination of) characteristics that most human artists would be hard-stretched to pull off,” said the firm’s CEO Park Ji-eun. “She can sing very well, rap very well and she can be creative as a (fashion) designer. And she’s a natural-born actress.”

    A video by Eternity ...


    https://us.cnn.com/style/kpop-virtua...hnk/index.html
    Fake Hanks ...

    Tom Hanks says dental plan video uses ‘AI version of me’ without permission

    Hollywood star Tom Hanks has “nothing to do with” an artificial intelligence version of himself that is promoting “some dental plan,” he said on Instagram on Sunday. ... Hanks also suggested on the same podcast that the technology could allow him to keep appearing in new movies after he dies.

    “Anybody can now recreate themselves at any age they are by way of AI or deep fake technology … I could be hit by a bus tomorrow and that’s it, but my performances can go on and on and on,” he added. ...

    https://us.cnn.com/2023/10/02/entert...cli/index.html
    AI make me Neurotic ...

    OpenAI is encouraging people to use ChatGPT for therapy. That’s dangerous.

    Just because a chatbot can recite language that appears therapeutic doesn’t mean its empathetic.


    This is a disconcerting development. That the company’s head of safety and its president are encouraging the public to think of a chatbot as a way to get therapy is surprising and deeply reckless. OpenAI profits from exaggerating and misleading the public about what its technology can and can’t do — and that messaging could come at the expense of public health.

    Weng’s language anthropomorphized ChatGPT by talking about feeling “heard” and “warm,” implying the AI has an ability to listen and understand emotions. In reality, ChatGPT’s humanlike language emerges from its ultra-sophisticated replication of language patterns that draws from behemoth databases of information. This capability is robust enough to help ChatGPTS users conduct certain kinds of research, brainstorm ideas and write essays in a manner that resembles a human. But that doesn’t mean it’s capable of performing many of the cognitive tasks of a human. Crucially, it cannot empathize with or understand the inner life of a user; it can at best only mimic how one might do so in response to specific prompts.

    https://www.msnbc.com/opinion/msnbc-...nai-rcna118058
    Lighting up the brain ...

    Theta-burst transcranial magnetic stimulation treatment could reduce cigarette cravings.

    A recent study from the University of Missouri School of Medicine indicates a potential alternative method to address cigarette cravings.

    The research demonstrates that by using theta-burst transcranial magnetic stimulation (TBS) – powerful and quickly changing magnetic pulses that influence brain activity – individuals may experience enhanced self-control, diminished cravings, and subsequently, decreased cigarette consumption.

    https://scitechdaily.com/goodbye-cig...ne-dependence/
    We share genes with vegetables too ...

    Being a vegetarian might be in your DNA

    The study published Wednesday in PLOS One found that there are four genes associated with how well someone is able to adhere to a vegetarian lifestyle.

    “At this time we can say is that genetics plays a significant role in vegetarianism and that some people may be genetically better suited for a vegetarian diet than others,” said lead study author Dr. Nabeel Yaseen, professor emeritus of pathology at Northwestern University’s Feinberg School of Medicine.

    https://us.cnn.com/2023/10/04/health...ess/index.html
    Gassho, J

    stlah
    Last edited by Jundo; 10-05-2023, 03:44 PM.

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  • Jundo
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    A rather silly article, but I like the advice ...

    Black holes can teach us how to live our best lives

    ... One such researcher is Priyamvada Natarajan, an astrophysicist and the chair of the astronomy department at Yale University. Natarajan studies supermassive black holes. These are black holes that are at the center of almost all galaxies whose masses range from over a hundred thousand Suns to a few billion. And after talking with Natarajan about the science of black holes, I realized that these enigmatic objects are actually overflowing with valuable life lessons.

    Lesson One: Push the limits, even if others doubt you

    Lesson Two: Reputation isn't everything

    Lesson Three: Do your thing, whether people get you or not

    https://www.npr.org/2023/10/05/12037...t-life-lessons
    The connection to black holes is a bit of a stretch (the same thing that happens if you fall in one! ), but sound advice nonetheless.

    Gassho J

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  • Jundo
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    Start packing, we only have 250 million years more. But, I suspect, we won't be on the planet by then, or will find a way to fine tune the sun and volcanoes. 250 million years is a long time, after all ...

    A study predicts a mass extinction of mammals in 250 million years due to extreme heat from the formation of a supercontinent.

    The research highlights the lethal combination of a hotter sun, increased CO2, and continental effects, underscoring the importance of landmass layouts in evaluating the habitability of exoplanets.

    Unprecedented heat is likely to lead to the next mass extinction since the dinosaurs died out, eliminating nearly all mammals in some 250 million years’ time, according to a new study.

    The research, published on September 25 in the journal Nature Geoscience and led by the University of Bristol, presents the first-ever supercomputer climate models of the distant future and demonstrates how climate extremes will dramatically intensify when the world’s continents eventually merge to form one hot, dry and largely uninhabitable supercontinent.

    The findings project how these high temperatures are set to further increase, as the sun becomes brighter, emitting more energy and warming the Earth. Tectonic processes, occurring in the Earth’s crust and resulting in supercontinent formation would also lead to more frequent volcanic eruptions which produce huge releases of carbon dioxide into the atmosphere, further warming the planet.

    Mammals, including humans, have survived historically thanks to their ability to adjust to weather extremes, especially through adaptations such as fur and hibernating in the cold, as well as short spells of warm weather hibernation.

    While mammals have evolved to lower their cold temperature survivable limit, their upper-temperature tolerance has generally remained constant. This makes exposure to prolonged excessive heat much harder to overcome and the climate simulations, if realized, would ultimately prove unsurvivable.

    BELOW: This image shows the geography of today's Earth and the projected geography of Earth in 250 million years, when all the continents converge into one supercontinent




    and

    https://us.cnn.com/2023/09/26/world/...scn/index.html
    But in the shorter term, although we won't be wiped out as a species, still great concerns ...

    Breaching the Limit: Global Concerns Rise As Six Key Planetary Boundaries Are Exceeded

    A new study updates the planetary boundary framework and shows human activities are increasingly impacting the planet and, thereby, increasing the risk of triggering dramatic changes in overall Earth conditions.

    For over 3 billion years, the interaction between life (represented by the planetary boundary, Biosphere Integrity) and climate have controlled the overall environmental conditions on Earth. Human activities, for example replacing nature with other land uses, changing the amount of water in rivers and in soil, the introduction of synthetic chemicals to the open environment, and the emission of greenhouse gases to the atmosphere all influence these interactions. ... The nine “planetary boundaries” represent components of the global environment that regulate the stability and liveability of the planet for people. The degree of breaching of the safe boundary levels is caused by human-driven activities impacting the components. The planetary boundaries framework applies the newest scientific understanding of the functioning of the Earth system to identify a ”safe operating space” for humanity by proposing limits for the extent to which human activities can be allowed to impact critical processes without risk of potentially triggering irreversible changes in the Earth conditions that support us.

    ... “Crossing six boundaries in itself does not necessarily imply a disaster will ensue but it is a clear warning signal. We can regard it as we do our own blood pressure. A BP over 120/80 is not a guarantee of a heart attack but it increases the risk of one. Therefore, we try to bring it down. For our own – and our children’s – sakes we need to reduce the pressure on these six planetary boundaries.” ...


    https://scitechdaily.com/breaching-t...-are-exceeded/
    In happier news, we are slowly getting ready for that jump to the stars ...

    (Just a little note that the Japanese Space Agency, JAXA, already accomplished this a couple of years ago, so this is only a milestone for NASA ... )

    Astrophysicist explains why NASA milestone is 'incredible'

    NASA returned its first ever asteroid sample to Earth seven years after launching into space. The OSIRIS-REx spacecraft flew by Earth to deliver the pristine sample from the near-Earth asteroid Bennu.


    More here: https://www.npr.org/2023/09/24/12013...-back-to-earth

    NASA is also making waves here ...

    NASA’s Cosmic Vision: Simulating Our Galaxy Through Gravitational Waves

    Using simulated data, astronomers have depicted the sky through gravitational waves, revealing the need for space observatories to detect binary systems. Future projects like LISA aim to uncover thousands of these hard-to-detect systems, marking a paradigm shift in space observation. (Artist’s illustration — see video below for simulation.)

    Astronomers using simulated data have produced a glimpse of the sky as it would appear in gravitational waves, cosmic ripples in space-time generated by orbiting objects. The image shows how space-based gravitational wave observatories expected to launch in the next decade will enhance our understanding of our galactic home.

    BELOW: Watch as gravitational waves from a simulated population of compact binary systems combine into a synthetic map of the entire sky. Such systems contain white dwarfs, neutron stars, or black holes in tight orbits. Maps like this using real data will be possible once space-based gravitational wave observatories become active in the next decade. Brighter spots indicate sources with stronger signals and lighter colors indicate those with higher frequencies. Larger colored patches show sources whose positions are less well known. The inset shows the frequency and strength of the gravitational signal, as well as the sensitivity limit for LISA (Laser Interferometer Space Antenna), an observatory now being designed by ESA (European Space Agency) in collaboration with NASA for launch in the 2030s. Credit: NASA’s Goddard Space Flight Center


    https://scitechdaily.com/nasas-cosmi...ational-waves/
    And more music of the spheres ...

    Stellar Concert: Astronomers Tune In to the Sounds of Twinkling Stars

    Northwestern University scientists have developed the first 3D simulations to study the energy rippling from a massive star’s core to its outer surface, providing new insights into stars’ inherent ‘twinkle’.


    The team also converted these waves into sound, enabling listeners to ‘hear’ the inside of a star and its natural twinkle.


    Merging Black Holes ...

    Using new simulation technology, scientists predict the existence of massive merging black holes in Milky Way-like galaxies, challenging established theories.

    ... Stellar-mass black holes are celestial objects born from the collapse of stars with masses of a few to low hundreds of times that of our sun. Their gravitational field is so intense that neither matter nor radiation can evade them, making their detection exceedingly difficult. Therefore, when the tiny ripples in spacetime produced by the merger of two black holes were detected in 2015, by the Laser Interferometer Gravitational-wave Observatory (LIGO), it was hailed as a watershed moment. According to astrophysicists, the two merging black holes at the origin of the signal were about 30 times the mass of the sun and located 1.5 billion light-years away. What mechanisms produce these black holes? Are they the product of the evolution of two stars, similar to our sun but significantly more massive, evolving within a binary system? Or do they result from black holes in densely populated star clusters running into each other by chance? Or might a more exotic mechanism be involved? All of these questions are still hotly debated today.

    ... “Models prior to POSYDON predicted a negligible formation rate of merging binary black holes in galaxies similar to the Milky Way, and they particularly did not anticipate the existence of merging black holes as massive as 30 times the mass of our sun. POSYDON has demonstrated that such massive black holes might exist in Milky Way-like galaxies” ...

    https://scitechdaily.com/challenging...f-black-holes/
    A possible hint of life in Europe ... I mean, on "Europa" ...

    Webb spots a building block of life on Jupiter’s moon Europa

    Two independent teams of astronomers used the James Webb Space Telescope to observe the frozen surface of Europa, and each analysis of the space observatory’s detections revealed an abundance of carbon dioxide within a specific region of the frigid terrain. Both studies describing the findings were published September 21 in the journal Science. ... Europa is one of several ocean worlds in our solar system besides Earth where scientists believe life could exist. Beneath a thick ice shell, Europa harbors a subsurface global ocean that may contain twice as much water as our planet’s oceans.

    But environments suitable for life need more than water — they also require a supply of organic molecules and an energy source, according to NASA. “We now think that we have observational evidence that the carbon we see on Europa’s surface came from the ocean. That’s not a trivial thing. Carbon is a biologically essential element,” said Samantha Trumbo, lead author of the second study and a 51 Pegasi B Fellow at Cornell University, in a statement. Scientists have long questioned whether Europa’s ocean contained carbon and other chemicals necessary for life. ...

    https://us.cnn.com/2023/09/27/world/...scn/index.html
    Building blocks in deep space too ...

    Never Before Detected – Organic Molecule Essential for Life Found in Interstellar Space

    Tryptophan is among the 20 vital amino acids necessary for protein synthesis, crucial for life’s evolution on Earth. This amino acid has many spectral features in the infrared, as had been previously characterized by Susana Iglesias Groth, an IAC researcher.

    Utilizing data from the Spitzer Space Observatory, she identified over 10 emission bands for this molecule, the strongest according to her laboratory measurements. ... The study presents evidence that tryptophan-associated emission lines may also be present in other star-forming regions and suggests that its presence, and possibly that of other amino acids, is common in the gas from which stars and planets form. “It is likely that amino acids, the building blocks of proteins, may be enriching the gas in the protoplanetary discs and atmospheres of young, newly formed exoplanets and perhaps accelerating the emergence of life there,” says Iglesias-Groth. ...

    ... “It is well known that amino acids are part of meteorites and may have been present as early as the formation of the Solar System” explains Iglesias-Groth. “The discovery of tryptophan and, hopefully, of other amino acids in the future, could indicate that protein-building agents, which are key to the development of living organisms, exist naturally in the regions where stars and planetary systems form, and that life may be more common in our Galaxy than we could have predicted” she concludes ...


    https://scitechdaily.com/never-befor...stellar-space/
    And more ways to look into space are coming ...

    Constructing the World’s Largest Optics: The Giant Magellan Telescope’s Final Mirror Fabrication Begins

    The Giant Magellan Telescope is finalizing its last primary mirror, with the goal to surpass current space telescopes in sensitivity and resolution. ... Together, the mirrors will collect more light than any other telescope in existence, allowing humanity to unlock the secrets of the Universe by providing detailed chemical analyses of celestial objects and their origin. ...

    ... Last week, the University of Arizona Richard F. Caris Mirror Lab closed the lid on nearly 20 tons of the purest optical glass inside a one-of-a-kind oven housed beneath the stands of the Arizona Wildcats Football Stadium. The spinning oven will heat the glass to 1,165°C (2,129°F) so as it melts, it is forced outward to form the mirror’s curved paraboloid surface. Measuring 8.4 meters (26.7 feet) in diameter—about two stories tall when standing on edge—the mirror will cool over the next three months before moving into the polishing stage.


    https://scitechdaily.com/constructin...cation-begins/
    Now, from the very vast to the very small ...

    Unveiling the Quantum World: Scientists Capture Quantum Entanglement of Photons in Real-Time

    Researchers have pioneered a technique for swiftly and efficiently reconstructing the full quantum state of entangled particles, utilizing advanced camera technology to visualize the wave function of two entangled photons in real time. The innovative method is exponentially faster than previous ones, taking minutes or seconds instead of days, and holds the potential for advancing quantum technology by enhancing quantum state characterization, quantum communication, and quantum imaging techniques.

    https://scitechdaily.com/unveiling-t...-in-real-time/
    No antimatter anti-gravity levitation! There goes my anti-matter hoverboard!

    Antimatter Levitation Debunked: Groundbreaking CERN Experiment Reveals Gravity’s Pull on Antihydrogen

    An experiment by the ALPHA collaboration at CERN has shown that antihydrogen, a combination of an anti-proton and an antielectron, is pulled downward by gravity, dispelling the idea of antigravity for antimatter. This aligns with Einstein’s general relativity theory, which predates antimatter’s discovery and suggests that all matter, regular or anti, reacts identically to gravitational forces.

    ... “The bottom line is that there’s no free lunch, and we’re not going to be able to levitate using antimatter.” ...

    ... Nevertheless, the idea that antimatter and matter might be affected differently by gravity was enticing because it could potentially explain some cosmic conundrums. For example, it could have led to the spatial separation of matter and antimatter in the early universe, explaining why we see only a small amount of antimatter in the universe around us. Most theories predict that equal amounts of matter and antimatter should have been produced during the Big Bang that birthed the universe. ...



    Maybe genetics can help us adapt to the new super hot super-continent??

    Scientists Successfully Genetically Modify Individual Cells in Living Animals

    Researchers have developed a technique using CRISPR-Cas to simultaneously modify multiple genes in the cells of adult animals, creating a mosaic-like pattern that simplifies studying genetic diseases. This approach has uncovered new insights into the genetic disorder 22q11.2 deletion syndrome and holds the potential to decrease the number of animal experiments in the future. Credit: ETH Zurich

    One proven method for tracking down the genetic origins of diseases is to knock out a single gene in animals and study the consequences this has for the organism. The problem is that for many diseases, the pathology is determined by multiple genes, complicating the task for scientists trying to pinpoint the contribution of any single gene to the condition. To do this, they would have to perform many animal experiments – one for each desired gene modification.

    Researchers led by Randall Platt, Professor of Biological Engineering at the Department of Biosystems Science and Engineering at ETH Zurich in Basel, have now developed a method that will greatly simplify and speed up research with laboratory animals: using the CRISPR-Cas gene scissors, they simultaneously make several dozen gene changes in the cells of a single animal, much like a mosaic.

    While no more than one gene is altered in each cell, the various cells within an organ are altered in different ways. Individual cells can then be precisely analyzed. This enables researchers to study the ramifications of many different gene changes in a single experiment.

    https://scitechdaily.com/scientists-...iving-animals/
    It is sometime good to marry your cousin ...

    A Genetic Paradox: Inbreeding Can Be Beneficial in the Long Run

    Despite the challenges of inbreeding and limited genetic diversity, the Svalbard reindeer have remarkably adapted to harsh living conditions in an extraordinarily short period, a situation researchers term a genetic paradox. However, the question remains: can they withstand the impacts of climate change?

    ... Evolutionary theory suggests this is a poor starting point since inbreeding can quickly lead to an accumulation of harmful mutations and genetic variants followed by disease and death. But this has not prevented the Svalbard reindeer from evolving into what is today a viable population of more than 20,000 animals. “Despite the low genetic diversity, they have managed to develop a number of adaptations to life in the High Arctic. They are, for example, smaller in size and have shorter legs than other northern reindeer and caribou subspecies,” says Dussex. ... “In this case, we are dealing with a population that suffers from a high degree of inbreeding, which is usually bad news for a small population. But inbreeding can also help a population to get rid of harmful mutations, a phenomenon technically called ‘purging’,” says Martin. ...

    [But] It is far from certain that the Svalbard reindeer will be able to adapt as well to the rapid changes that result from global warming. The adaptations the reindeer have developed for the extreme arctic climate may fall short as the archipelago is now rapidly warming, which is changing both snow cover and vegetation. ...

    https://scitechdaily.com/a-genetic-p...-the-long-run/
    Well, we can't survive the hot age, but got through the ice age ...

    Unraveling an Ice Age Mystery – New Study Reveals Surprises About Early Human Migration

    A recent study analyzed pollen data around Lake Baikal in Siberia to uncover details about early human migration across Europe and Asia 45,000-50,000 years ago. The evidence suggests that warming temperatures supported expanding forests, facilitating human migration into Siberia, and contradicting some previous archaeological perspectives.

    ... the pollen data suggest that the dispersal of people occurred during some of the highest temperatures in the late Pleistocene, which also would have featured higher humidity. The ancient pollen record shows coniferous forests and grasslands characterized the region, able to support foraging and hunting by humans. Goebel said the environmental data, combined with archeological evidence, tell a new story.

    “This contradicts some recent archaeological perspectives in Europe,” said the KU researcher. “The key factor here is accurate dating, not just of human fossils and animal bones associated with the archaeology of these people, but also of environmental records, including from pollen. What we have presented is a robust chronology of environmental changes in Lake Baikal during this time period, complemented by a well-dated archaeological record of Homo sapiens’ presence in the region.” ...

    BELOW: Map showing theorized migration routes of early Homo sapiens from Africa across Eurasia.


    https://scitechdaily.com/unraveling-...man-migration/
    Mysteries and discoveries still remain right here on earth ...

    Scientists Discover New Insect Genus in Peruvian Rainforest

    Capitojoppa amazonica is a large parasitoid wasp species that has only been discovered in the Allpahuyao-Mishana National Reserve in the Peruvian Amazon. Here, the wasp is photographed from the front.


    https://scitechdaily.com/scientists-...an-rainforest/
    We won't need sex soon ... or, on the brighter side, anyone soon can have a child ... fairly soon, anyway ...

    Japanese scientists race to create human eggs and sperm in the lab

    ... Hayashi, a developmental geneticist at Osaka University in Japan, is a pioneer in one of the most exciting — and controversial — fields of biomedical research: in vitro gametogenesis, or IVG.

    The goal of IVG is to make unlimited supplies of what Hayashi calls "artificial" eggs and sperm from any cell in the human body. That could let anyone — older, infertile, single, gay, trans — have their own genetically related babies. Besides the technical challenges that remain to be overcome, there are deep ethical concerns about how IVG might eventually be used. ... IPS cells can be made from any cell in the body and then theoretically can morph into any other kind of cell. This versatility could one day help scientists solve a long list of medical problems.

    Hayashi was the first to figure out how to use iPS cells to make one of the first big breakthroughs in IVG: He turned skin cells from the tails of mice into iPS cells that he then turned into mouse eggs. ...

    ... Researchers at a biotech startup called Conception, based in California, claim they're about to lap the Japanese scientists. Within a year, they say they'll be ready to make human eggs they hope to try to fertilize to make human embryos. But the Americans have released few details to back up their claim.

    Hayashi's skeptical.

    "It's impossible," Hayashi says. "In my opinion — one year — I don't think so."

    Unraveling the biology of human egg development just doesn't move that fast, he says.

    That said, Hayashi thinks it's not a question if IVG will ever happen. It's more a question of when, he says, and that he and his colleagues in Japan are at least as close as the Americans to making "artificial" human embryos.

    Hayashi predicts they'll have an IVG egg ready to try to fertilize within five to 10 years. ...

    ... In addition to waiting to publish their research before making any claims, the Japanese scientists also warn that many years of experimentation would be needed to make sure artificial IVG embryos aren't carrying dangerous genetic mutations.

    "They may cause some sort of diseases, or maybe cancer, or maybe early death. So there are many possibilities," Saitou says. "Even single mutations or mistakes are really disastrous." ...

    ... IVG would render the biological clock irrelevant, by enabling women of any age to have genetically related children. That raises questions about whether there should be age limits for IVG baby-making.

    IVG could also enable gay and trans couples to have babies genetically related to both partners, for the first time allowing families, regardless of gender identity, to have biologically related children.

    Beyond that, IVG could potentially make traditional baby-making antiquated for everyone. An unlimited supply of genetically matched artificial human eggs, sperm and embryos for anyone, anytime could make scanning the genes of IVG embryos the norm.

    Prospective parents would be able to minimize the chances their children would be born with detrimental genes. IVG could also lead to "designer babies," whose parents pick and choose the traits they desire.

    "That [would] mean maybe exploitation of embryos, commercialization of reproduction. And also you could manipulate genetic information of those sperm and egg," says Misao Fujita, a bioethicist at the University of Kyoto who's been studying Japanese public opinion about IVG.

    The Japanese public is uncomfortable with IVG for those reasons. But the Japanese would even be uneasy about using this technology to create babies outside of traditional family structures, she says.

    "If you can create artificial embryos, then that mean[s] maybe a single person can create their own baby. So who is [the] mother and father? So that means social confusion," Fujita says.

    They're leading in the development of IVG, new fertility technology that could make sperm and eggs from practically any cell in the body. The results could transform human reproduction.

    Maybe after the mammals are gone, AI will replace us ... or figure out how to save us ...

    ChatGPT can now see, hear, and speak

    We are beginning to roll out new voice and image capabilities in ChatGPT. They offer a new, more intuitive type of interface by allowing you to have a voice conversation or show ChatGPT what you’re talking about.

    Voice and image give you more ways to use ChatGPT in your life. Snap a picture of a landmark while traveling and have a live conversation about what’s interesting about it. When you’re home, snap pictures of your fridge and pantry to figure out what’s for dinner (and ask follow up questions for a step by step recipe). After dinner, help your child with a math problem by taking a photo, circling the problem set, and having it share hints with both of you.




    ChatGPT’s voice capability is “powered by a new text-to-speech model, capable of generating human-like audio from just text and a few seconds of sample speech,” Open AI said in the blogpost. The company added that it collaborated with professional voice actors to create the five different voices that can be used to animate the chatbot. ... The new features roll out in the app within the next two weeks for paying subscribers of ChatGPT’s Plus and Enterprise services. (Subscriptions to the Plus service are $20 a month, and its Enterprise service is currently only offered to business clients).


    And getting smarter ...

    100x Efficiency: MIT’s Machine-Learning System Based on Light Could Yield More Powerful Large Language Models

    MIT system demonstrates greater than 100-fold improvement in energy efficiency and a 25-fold improvement in compute density compared with current systems.

    ChatGPT has made headlines around the world with its ability to write essays, email, and computer code based on a few prompts from a user. Now an MIT-led team reports a system that could lead to machine-learning programs several orders of magnitude more powerful than the one behind ChatGPT. The system they developed could also use several orders of magnitude less energy than the state-of-the-art supercomputers behind the machine-learning models of today.

    https://scitechdaily.com/100x-effici...nguage-models/
    But the humans are still ahead ... for now ...

    Radiologists vs. Robots: Outperforming AI in Identifying Lung Diseases on Chest X-Rays

    Radiologists surpassed AI in accurately detecting three common lung diseases from chest X-rays, as per a study in the Radiology journal. AI tools, while sensitive, produced more false positives, making them less reliable for autonomous diagnoses but useful for second opinions.

    https://scitechdaily.com/radiologist...-chest-x-rays/
    AI is already doing so good things, however imperfectly ...

    Revolutionary AI Set To Predict Your Future Health With a Single Click

    Researchers from Edith Cowan University developed software that rapidly analyzes bone density scans to detect abdominal aortic calcification (AAC), a predictor of cardiovascular events and other health risks. The software processed images with 80% agreement with experts and could revolutionize early disease detection during routine clinical practice.

    https://scitechdaily.com/revolutiona...-single-click/
    This is AI HUGE!

    Paralyzed man regains some [Hand] function after world-first surgery

    A 46-year-old Swiss man who was paralyzed after a devastating fall has regained some movement following groundbreaking surgery that appeared to successfully install an implant on his brain using artificial intelligence.

    A 46-year-old Swiss man who was paralyzed after a devastating fall has regained some movement following groundbreaking surgery that appeared to successfully install an implant on his brain using artificial intelligence. CNN’s Nick Watt reports.


    Paralyzed Man Can Use Feel Again Thanks to Groundbreaking AI

    AI can often more understanding of human behavior and movement ...

    GlowTrack: Unleashing the Power of AI To Track Human and Animal Behavior

    Current cutting-edge methods utilize artificial intelligence to automatically track parts of the body as they move. However, training these models is still time-intensive and limited by the need for researchers to manually mark each body part hundreds to thousands of times.

    Now, Associate Professor Eiman Azim and team have created GlowTrack, a non-invasive movement-tracking method that uses fluorescent dye markers to train artificial intelligence. GlowTrack is robust, time-efficient, and high definition—capable of tracking a single digit on a mouse’s paw or hundreds of landmarks on a human hand.

    https://scitechdaily.com/glowtrack-u...imal-behavior/
    But AI can also track and spy on us in other ways ...

    Exposing the secretive company at the forefront of facial recognition technology

    Facial recognition technology is convenient when you use it to unlock your phone or log into an app. But you might be surprised to know that your face is most likely already in a facial recognition database that can be used to identify who you are without you even being aware it's happening or knowing who's using it and why.

    A company expanding the technological possibilities of this technology and testing its legal and ethical limits is Clearview AI. It's a startup whose clients already include some law enforcement and government agencies. If you haven't already heard of it, it's in part because the company didn't want you to know it existed. It did its best to remain secretive until it was exposed by my guest, Kashmir Hill. She's a New York Times tech reporter who first wrote about Clearview AI in 2020. She describes her beat as the future tech dystopia and how we can try to avoid it. Kashmir has continued to report on Clearview AI and other developments in facial recognition technology. Now, she has a new book called "Your Face Belongs To Us: A Secretive Startup's Quest To End Privacy As We Know It."

    ... For police use of this technology, you know, it can be very useful for solving crimes, but, you know, it can also be wielded in a way that could be very chilling or intimidating. Say, if there are protesters against police brutality and the government is able to very easily identify them. And we have seen this already happen in other countries, not with Clearview AI's technology but with other facial recognition technology. In China, you know, this kind of technology has been used to identify protesters in Hong Kong, to identify Uyghur Muslims and for more surprising uses like naming and shaming people who wear pajamas in public or making sure that somebody in a public restroom doesn't take too much toilet paper. They have to look at a face recognition camera, only get a little bit of toilet paper and then wait a certain amount of time until their face can unlock more. ...

    JUNDO: A fascinating interview, highly recommended:

    NYT reporter Kashmir Hill says Clearview AI has a database of billions of photos scraped from the internet, which it sells to governments and police departments. Her book is Your Face Belongs To Us.

    AI and automation might help places like Japan with a labor shortage, but also unemployment caused by AI!!!

    Japan labor market set for change as huge worker shortage looms

    Japan's labor market may be at an inflection point as the nation braces for a shortfall of millions of workers, the rise of generative AI and risks to economic security. ... In the short term, labor shortages are evident in the pandemic-hit services sector, with labor-intensive areas like nursing care and construction already struggling. ... The institute estimates 9.7 million jobs will be lost by 2035 due to the effects of digitalization, including AI. But labor will still be in short supply that year as a result of a push for green and digital transformations and efforts to boost the nation's semiconductor industry. ... One challenge for the broader Japanese labor market is that the percentage of workers with non-routine, or "creative," tasks in relation to routine ones is lower than in countries like the United States and Britain, the institute said, expecting a severe labor shortage for professional technical occupations. ...
    The International Labor Organization says generative AI, which is neither inherently good nor bad, will "augment" rather than destroy jobs. The U.N. agency is calling for governments and others to design the right policies to ensure a smooth transition because costs to affected workers will be "brutal." ...
    https://mainichi.jp/english/articles...0m/0bu/037000c
    Hopefully, we will regulate AI better than the internet ... doubtful ...

    FCC [in USA] to reintroduce rules protecting net neutrality

    he US government aims to restore sweeping regulations for high-speed internet providers such as AT&T, Comcast and Verizon, reviving “net neutrality” rules for the broadband industry — and an ongoing debate about the internet’s future.

    The proposed rules from the Federal Communications Commission will designate internet service — both the wired kind found in homes and businesses as well as mobile data on cellphones — as “essential telecommunications” akin to traditional telephone services, said FCC Chairwoman Jessica Rosenworcel. The rules would ban internet service providers (ISPs) from blocking or slowing down access to websites and online content.

    In addition to the prohibitions on blocking and throttling internet traffic, the draft rules also seek to prevent ISPs from selectively speeding up service to favored websites or to those that agree to pay extra fees, Rosenworcel said, a move designed to prevent the emergence of “fast lanes” on the web that could give some websites a paid advantage over others.

    https://us.cnn.com/2023/09/26/tech/f...ers/index.html
    Maybe we will handle AI better than atomic weaponry ... which, sadly, is far from over ...

    Birthplace of atomic bomb braces for biggest mission since the Manhattan Project

    The community is facing growing pains as Los Alamos National Laboratory takes part in the country’s most ambitious nuclear weapons effort since World War II


    ... 80 years later, as Los Alamos National Laboratory takes part in the nation’s most ambitious nuclear weapons effort since World War II. The mission calls for modernizing the arsenal with droves of new workers producing plutonium cores — key components for nuclear weapons. ...

    https://www.nbcnews.com/news/us-news...ect-rcna117097
    Gassho, J

    stlah
    Last edited by Jundo; 09-30-2023, 06:25 AM.

    Leave a comment:


  • Jundo
    replied
    Part man part pig part man ...

    Groundbreaking transplant of pig heart into living recipient is performed for the second time ever

    ... The groundbreaking surgery was done on September 20 at UMMC by the same transplant team that preformed the first such experimental surgery in 2022.

    In a news release, the hospital said the recipient, 58-year-old Lawrence Faucette, “is currently breathing on his own, and his heart is functioning well without any assistance from supportive devices.” ... Faucette had end-stage heart disease. He had pre-existing peripheral vascular disease and complications with internal bleeding making him ineligible for a traditional heart transplant, the hospital said in the release. ...

    ... The pig heart used came from a genetically modified pig from Revivcor, a subsidiary the United Therapeutics Corporation. The pig had 10 genes edited, including three genes “knocked out” or inactivated to eliminate the alpha gal sugar in the pig’s blood cells, which can trigger a severe reaction in the human immune system, causing organ rejection. An additional pig gene was modified to control for the growth of the pig’s heart while 6 human genes were added into the pig’s genome to increase acceptance by the immune system. ...


    https://us.cnn.com/2023/09/22/health...ver/index.html
    This hit me in the kidneys ...

    Scientists Discover a Previously Unknown “Housekeeping” Process in Kidney Cells

    ... scientists discovered a unique “housekeeping” process in kidney cells where unwanted content is ejected, rejuvenating the cells. This mechanism, different from typical regeneration in other organs, could explain why kidneys stay healthy for a lifetime. ...

    ... Unlike the liver and skin, where cells divide to create new daughter cells and regenerate the organ, cells in the proximal tubules of the kidney are mitotically quiescent — they do not divide to create new cells. In cases of a mild injury or disease, kidney cells do have limited repair capabilities, and stem cells in the kidney can form new kidney cells, but only up to a point, said Dr. Jie Zheng ... The researchers found proximal tubular cells that had formed outwardly facing bulges in their luminal membranes that contained not only gold nanoparticles but also lysosomes, mitochondria, endoplasmic reticulum, and other organelles typically confined to a cell’s interior. The extruded contents were then pinched off into a vesicle that floated off into the extracellular space.

    “At that moment, we knew this was an unusual phenomenon,” Yu said. “This is a new method for cells to remove cellular contents.”

    https://scitechdaily.com/sweeping-di...-kidney-cells/
    One more piece of the puzzle ...

    A source of carbon — a building block of life — is found on Jupiter's moon Europa

    In an intriguing breakthrough, astronomers have concluded that carbon, an essential component of life on Earth, is also present within Europa, Jupiter's ice-covered moon that's believed to hold huge oceans of liquid salt water beneath its icy surface.

    The findings come from analyzing images from NASA's James Webb Space Telescope, which found the carbon "likely originated in the subsurface ocean," according to a summary of two papers about the analysis.

    "The discovery signals a potentially habitable environment in the ocean of Europa," according to the Webb telescope's website.

    ... [BUT] ... It's important to remember that in this context, a "habitable environment" on Europa refers to a salty ocean encased by an ice shell that's believed to be 10 to 15 miles thick, on a moon where the sunlight is about 25 times fainter than on Earth. If that's not enough to make you put away your swimsuit, consider the neighborhood bully: Europa is under the thrall of Jupiter's radiation and gravity — the latter is so strong, it's believed to create tides that rip the moon's thick ice crust apart.

    But NASA says tidal flexing on Europa could also produce the heat and nutrients that encourage life. So while the differences between conditions on Earth are stark, similarities, like the likely presence of carbon, are compelling. And while Europa is a bit smaller than our Moon, its ocean is estimated to hold more than twice as much water as all of Earth's oceans together.

    The new findings come a year before NASA's ambitious Europa Clipper mission, which will launch in October of 2024 and reach the Jovian moon in 2030.


    "The discovery signals a potentially habitable environment in the ocean of Europa," according to the Webb Space Telescope's website.
    Life recipes ... and carbon may not always be needed ...

    New Chemical Recipes for Life’s Origins: Guiding Us to Distant Planets Inhabited by Extraterrestrials

    Life on a faraway planet — if it’s out there — might not look anything like life on Earth. But there are only so many chemical ingredients in the universe’s pantry, and only so many ways to mix them. A team led by scientists at the University of Wisconsin–Madison has exploited those limitations to write a cookbook of hundreds of chemical recipes with the potential to give rise to life.

    Their ingredient list could focus the search for life elsewhere in the universe by pointing out the most likely conditions — planetary versions of mixing techniques, oven temperatures, and baking times — for the recipes to come together. ... “The origin of life really is a something-from-nothing process,” says Betül Kaçar, a NASA-supported astrobiologist and UW–Madison professor of bacteriology. “But that something can’t happen just once. Life comes down to chemistry and conditions that can generate a self-reproducing pattern of reactions.”



    ... The search for plausible prebiotic autocatalytic systems has been generally centered on carbon-mediated cycles because biological autocatalysis largely relies on organic substrates mediated by linear polymers, e.g., proteins and nucleic acids. No reason has been unequivocally enunciated, however, to ignore wholesale other elements and inorganic compounds that might have scaffolded life’s origins terrestrially or elsewhere in the cosmos. ...

    Bring em back alive ...

    Scientists recover RNA from an extinct species for the first time


    Geneticists have for the first time isolated and decoded RNA molecules from a creature that died out long ago.

    The genetic material — which came from a 130-year-old Tasmanian tiger, or thylacine, specimen in the collection of the Swedish Museum of Natural History in Stockholm — has allowed scientists to better understand how the animal’s genes functioned. The researchers shared their findings in a study published Tuesday in the scientific journal Genome Research. ... “We had previously thought only DNA remained in old museum and ancient samples, but this paper shows you can also get RNA from tissues,” ... Mármol Sánchez said that while de-extinction wasn’t the goal of his team’s research, a better understanding of the Tasmanian tiger’s genetic makeup could help recently launched efforts to bring back the animal in some form.

    Brains came ...

    Tiny Unique Sea Creatures Reveal the Ancient Origins of Neurons

    Approximately 800 million years ago, our brain cell components began to take shape in shallow seas.
    Research published in the journal Cell offers new insights into the evolution of neurons, focusing on the placozoans, a millimeter-sized marine animal. Scientists from the Centre for Genomic Regulation in Barcelona discovered that the specialized secretory cells in these ancient and unique animals may have given rise to neurons in more complex animals.

    ... Surprisingly, the peptidergic cells shared many similarities to neurons – a cell type that didn’t appear until many millions of years later in more advanced animals such as bilateria. ... “We were astounded by the parallels,” says Dr. Sebastián R. Najle, co-first author of the study and postdoctoral researcher at the Centre for Genomic Regulation. “The placozoan peptidergic cells have many similarities to primitive neuronal cells, even if they aren’t quite there yet. It’s like looking at an evolutionary stepping stone.”

    The dawn of the neuron
    The study demonstrates that the building blocks of the neuron were forming 800 million years ago in ancestral animals grazing inconspicuously in the shallow seas of ancient Earth. From an evolutionary point of view, early neurons might have started as something like the peptidergic secretory cells of today’s placozoans. ...

    What we have learned ...

    Scientists Discover That the Genes for Learning and Memory Are 650 Million Years Old

    Researchers have found that genes linked to complex behaviors like learning and aggression originated around 650 million years ago, potentially influencing the Cambrian Explosion. This discovery may provide insights into the origins of various complex behaviors in animals, including humans.


    A team of scientists led by researchers from the University of Leicester has determined that genes responsible for learning, memory, aggression, and other complex behaviors emerged approximately 650 million years ago.

    ... Dr. Feuda said: “We’ve known for a long time that monoamines like serotonin, dopamine, and adrenaline act as neuromodulators in the nervous system, playing a role in complex behavior and functions like learning and memory, as well as processes such as sleep and feeding.“However, less certain was the origin of the genes required for the production, detection, and degradation of these monoamines. Using the computational methods, we reconstructed the evolutionary history of these genes and showed that most of the genes involved in monoamine production, modulation, and reception originated in the bilaterian stem group. This finding has profound implications on the evolutionary origin of complex behaviors such as those modulated by monoamines we observe in humans and other animals.”

    The authors suggest that this new way to modulate neuronal circuits might have played a role in the Cambrian Explosion – known as the Big Bang – which gave rise to the largest diversification of life for most major animal groups alive today by providing flexibility of the neural circuits to facilitate the interaction with the environment.

    Dr. Feuda added: “This discovery will open new important research avenues that will clarify the origin of complex behaviors and if the same neurons modulate reward, addiction, aggression, feeding, and sleep.”

    https://scitechdaily.com/scientists-...ion-years-old/
    Boom ...

    Cosmic Enigma Decoded: World’s First 3D Simulations Reveal the Physics of Exotic Supernovae

    This image depicts the final physical distributions of the exotic supernova, with four distinct color quadrants representing different physical quantities: I. temperature, II. velocity, III. radiative energy density, and IV. gas density. The white dashed circle indicates the position of the supernova photosphere. From this image, the entire star becomes turbulent from the inside out. The positions where ejected materials collide closely match the photosphere, indicating the production of thermal radiation during these collisions, which efficiently propagates outward and simultaneously creates an uneven gas layer. This image helps us understand the underlying physics of exotic supernovae and provides an explanation for the observed phenomena.

    Old wood ...

    476,000 Years Ago: Archaeologists Discover World’s Oldest Wooden Structure

    Research from the University of Liverpool and Aberystwyth University reveals humans were constructing wooden structures 476,000 years ago at Kalambo Falls, Zambia. This discovery, dated using advanced techniques, highlights the early human capability to settle and challenges previous notions about Stone Age lifestyles. ... earlier than was previously thought possible ...

    ... Expert analysis of stone tool cut marks on the wood shows that these early humans shaped and joined two large logs to make a structure, probably the foundation of a platform or part of a dwelling. ... A digging stick and other wooden tools were found at the same site. ...




    https://us.cnn.com/2023/09/20/africa...scn/index.html
    Old shoe ...

    Archaeologists discover 2,000-year-old child’s shoe with laces intact


    A shoe belonging to a child and dating back more than 2,000 years has been unearthed in Austria with its laces still intact.

    The design of the leather shoe, whose size roughly corresponds to EU 30 (US 12), suggests it was likely made in the second century BC, according to the German Mining Museum Bochum-Leibniz Research Museum for Geo-resources.



    https://us.cnn.com/2023/09/20/world/...scn/index.html
    An AI Brain? A Brain AI?

    A new study bridging neuroscience and machine learning offers insights into the potential role of astrocytes in the human brain.

    Artificial neural networks are ubiquitous machine-learning models that can be trained to complete many tasks. Their name stems from the fact that their architecture is inspired by the way biological neurons process information in the human brain. Scientists discovered a new type of more powerful neural network model known as a transformer about six years ago. These models can achieve unprecedented performance, such as by generating text from prompts with near-human-like accuracy. A transformer underlies AI systems such as OpenAI’s ChatGPT and Google’s Bard, for example. While incredibly effective, transformers are also mysterious: Unlike with other brain-inspired neural network models, it hasn’t been clear how to build them using biological components.

    Bridging Biology and Transformers

    Now, researchers from MIT, the MIT-IBM Watson AI Lab, and Harvard Medical School have produced a hypothesis that may explain how a transformer could be built using biological elements in the brain. They suggest that a biological network composed of neurons and other brain cells called astrocytes could perform the same core computation as a transformer. ...

    ... Their hypothesis provides insights that could spark future neuroscience research into how the human brain works. At the same time, it could help machine-learning researchers explain why transformers are so successful across a diverse set of complex tasks. ...

    https://scitechdaily.com/neurons-ast...lly-plausible/
    I need AI to help me keep all the new AI straight in my mind ...

    Google’s Bard artificial intelligence chatbot is evolving.

    The company on Tuesday announced a series of updates to Bard that will give the chatbot access to Google’s full suite of tools — including YouTube, Google Drive, Google Flights and others — to assist users in a wider variety of tasks. Users will be able, for example, to ask Bard to plan an upcoming trip, complete with real flight options. Or a user could ask the tool to summarize meeting notes made in a recent Google Drive document.

    The connections to Google’s other services are just some of the improvements to Bard coming Tuesday. Other updates include the ability to communicate with the chatbot in multiple languages, new fact-checking capabilities and a broad update to the large language model that the tool is built on.

    https://us.cnn.com/2023/09/19/tech/g...tes/index.html
    Too much carbon ...

    70 Gigatonnes – Steel Plant Upgrades Could Save Equivalent of Two Years of Global Carbon Emissions

    Upgrading, or retrofitting, the world’s iron and steel processing plants early could reduce carbon emissions by up to 70 gigatonnes by 2050, which is roughly equivalent to two years’ worth of net global carbon emissions.

    ... The scientists discovered that as of 2019, the last year that data is available, 74.5% of the world’s steel was produced in coal-powered plants that release considerable carbon emissions. Technologies exist to reduce these admissions, but upgrades are expensive and time-consuming and so are usually only undertaken at the end of a processing unit’s operational lifetime.

    Refining is also hard on the equipment, and the individual processing units within each plant need to be retrofitted periodically to prolong their operational lifetimes. Overall, 43.2% of global iron and steel plants have been retrofitted with new technologies or have otherwise enhanced their processes to extend their operating lifetime. The frequency of their retrofits depends on the technique they employ and how old they are, but typically they occur after 15 to 27 years of use.

    The team found that if all currently operating processing units were upgraded to incorporate low-emissions technology at their predicted time of their refit, total emissions from the iron and steel sector could be reduced by 58.7 gigatonnes between 2020 and 2050, but if all the refits and upgrades were bumped forward and completed five years early, the total carbon savings would be 16% greater at 69.6 gigatonnes.

    https://scitechdaily.com/70-gigatonn...bon-emissions/
    China cuts off the world ...

    China just stopped exporting two minerals the world’s chipmakers need

    China’s exports of two rare minerals essential for manufacturing semiconductors fell to zero in August, a month after Beijing imposed curbs on sales overseas, citing national security.

    China produces about 80% of the world’s gallium and about 60% of germanium, according to the Critical Raw Materials Alliance, but it didn’t sell any of the elements on international markets last month, Chinese customs data released on Wednesday showed. In July, the country exported 5.15 metric tons of forged gallium products and 8.1 metric tons of forged germanium products. ... China may be the industry leader in producing the two elements, but there are alternative producers, as well as available substitutes for both materials, Eurasia Group analysts said in a July research report. ...

    https://us.cnn.com/2023/09/21/econom...hnk/index.html

    Gassho, J

    stlah
    Last edited by Jundo; 09-23-2023, 12:27 PM.

    Leave a comment:


  • Jundo
    replied
    Originally posted by Dan65
    Can you not be sectioned if you are judged a liability in the US? In the UK, if you show psychotic symptoms or similar, and are judged unfit by a psychiatrist you get forced into the psyche ward, essentially mandatory treatment, on the understanding that you are no longer fit to make a rational decision.

    Sattday

    Dan
    I think that, if you read the details of this, it is a little different in scope. I believe that you are speaking of civil commitment.

    When it comes to mental illness, the problem of when to treat people who don't know they need treatment or people who resist treatment is a tough one. For decades now, compelling people into care, something called involuntary commitment, has been deemphasized as an option and considered only as a last resort. The thinking is that the patient should have autonomy and participate in their care. But now Democratic states such as Oregon and California are reconsidering their approaches as mental health, the drug epidemic and also homelessness become increasingly political problems.

    ... The attention to this has really been rooted in homelessness, which is a huge problem in California. Half of the unsheltered population in the country lives here. And even though only a quarter or a third of those folks have a serious mental illness, that is where we're seeing a lot of policy proposals being directed. So this year the state is rolling out something called Care Courts. This is where a family member or a doctor can refer someone who has a psychotic illness to court. And a judge will draw up a care plan that the person is strongly encouraged to accept. Another recent proposal is to expand who qualifies for involuntary commitment. One doctor told me about a patient who's homeless who has both diabetes and schizophrenia, and he keeps cycling in and out of the emergency room because he's not taking his diabetes medication. And that's because he's not taking his antipsychotic medication. So right now doctors' hands are tied with a patient like this...

    ... Because being unable to take care of your own medical needs is not a reason that doctors can intervene under the current law, and that is something that they want to change. ...

    ... Why is changing civil commitment such a nonstarter in Oregon where, like, in California, they're honestly considering changing it? ... I think a few things are still different here [in California]. First, the power to force a civil commitment in Oregon is very narrow but maybe not quite as narrow as in California. So to take one of April's examples, in Oregon, a person who is not taking diabetes medication due to psychosis - that person could be successfully civilly committed. The legislature made a small change in 2015 that makes those cases a little easier to pursue. But there's real resistance to going further. And the biggest issue by far is treatment capacity for mental illness and substance use disorders. There's just limited political interest in forcing more people into treatment when the system can barely handle the patients it has right now. ... The state [Oregon] has two dedicated psychiatric hospitals with about 600 beds total. And over the last decade, more of those beds have been needed for people who are in county jails who are too mentally ill to understand the charges against them.

    So the result is that most civilly committed patients are denied a bed at the state hospital. And then there's no community beds, either. Like, sending someone to a nursing home or an adult foster home or a residential treatment facility - those beds were in really short supply already.

    https://www.npr.org/2023/03/28/11666...ary-commitment
    Gassho, J

    stlah

    Leave a comment:


  • Guest
    Guest replied
    Originally posted by Jundo
    A necessary step perhaps, but with ethical concerns to weigh ...

    In several California counties, new mental health courts open up in October. Officials hope to persuade people with psychosis to accept treatment. Critics say, it looks more like coercion.




    Gassho, J

    stlah
    Can you not be sectioned if you are judged a liability in the US? In the UK, if you show psychotic symptoms or similar, and are judged unfit by a psychiatrist you get forced into the psyche ward, essentially mandatory treatment, on the understanding that you are no longer fit to make a rational decision.

    Sattday

    Dan

    Leave a comment:


  • Jundo
    replied
    A necessary step perhaps, but with ethical concerns to weigh ...

    In several California counties, new mental health courts open up in October. Officials hope to persuade people with psychosis to accept treatment. Critics say, it looks more like coercion.


    AT NEW MENTAL HEALTH COURTS IN CALIFORNIA, JUDGES WILL BE ABLE TO MANDATE TREATMENT

    [NPR] For years, she refused help, insisting to all who offered, "I'm not sick," until police arrested her for petty theft and public drunkenness. A judge gave her an ultimatum: jail or treatment. She chose treatment.

    "I'm so thankful that they did that," said Sweeney, now 52. "I needed that. I think there's others out there that need it, too."

    If she hadn't been compelled to get care, Sweeney said, she wouldn't be alive today, back at work and reunited with her husband. It's why she supports California's new civil CARE Courts that will launch this fall in eight counties, including San Francisco, Los Angeles, and Orange, followed by the rest of the state in 2024.

    Under the new system, family members and first responders can ask county judges to order people with psychotic illness into treatment, even if they are not unhoused or haven't committed a crime.

    A judge will then determine if a person meets criteria for the program and may oversee a care agreement or compel a treatment plan. That treatment plan could even include involuntary commitment.

    ... That tension — between those who advocate for treatment being voluntary and those who say the status quo allows people to die in the streets "with their rights on" — is playing out all over the state of California.
    Gassho, J

    stlah

    Leave a comment:


  • Jundo
    replied
    I might sometimes sound a bit "out there" for talking about how we had best use some of this tech, and what Zen and Buddhism have to say about doing so ...

    ... but I am not so "out there." This from today's news.

    Just what we all need: Elon Musk and X in our heads!


    Neuralink, Elon Musk’s brain implant startup, set to begin human trials

    After receiving approval from an independent review board, Neuralink is set to begin offering brain implants to paralysis patients as part of the PRIME Study, the company said. PRIME, short for Precise Robotically Implanted Brain-Computer Interface, is being carried out to evaluate both the safety and functionality of the implant.

    Trial patients will have a chip surgically placed in the part of the brain that controls the intention to move. The chip, installed by a robot, will then record and send brain signals to an app, with the initial goal being “to grant people the ability to control a computer cursor or keyboard using their thoughts alone,” the company wrote.

    ... In his new book about Neuralink’s founder, author Walter Isaacson reported that Musk was inspired by science fiction authors such as Iain Banks to pursue a “human-machine interface technology called ‘neural lace’ that is implanted into people and can connect all of their thoughts to a computer.” ...

    ... But employees told Reuters in December that the company is rushing to market, resulting in careless animal deaths and a federal investigation.

    Neuralink did not respond to CNN’s request for comment.

    https://us.cnn.com/2023/09/20/tech/m...als/index.html

    Gassho, J

    stlah

    Leave a comment:


  • Jundo
    replied
    And an article which merits a special mention...

    Near-death experiences tied to brain activity after death, study says

    ... Parnia is the senior author of a new study designed to uncover what he calls the “hidden consciousness” of death by measuring electrical activity in the brain when the heart stops and breathing ceases. PMany people report the same experience. Their consciousness became heightened and more vivid, and their thinking became sharper and clearer all while doctors like myself are trying to revive them and think they’re dead,” said Parnia, an associate professor at NYU Grossman School of Medicine in New York City. “They have a sensation they have separated from the body and can see and hear doctors and nurses, and they were able to report what doctors were doing to them in a 360-degree way that’s inexplicable to them,” he added.

    In addition, people often review their entire lives, remember thoughts, feelings and events they normally couldn’t, and begin to evaluate themselves based upon principles of morality and ethics. It’s a “global comprehension of their behavior throughout life where they can no longer deceive themselves,” Parnia said. People also report seeing a God-like being Parnia says can be interpreted in different ways: “If you happen to be a Christian, you say, ‘I saw Jesus’ and if you happen to be an atheist, you say ‘I saw this incredible being of love and compassion.’ All of this has been reported now for more than 60 years.”

    ... In the study, published Thursday in the journal Resuscitation, teams of trained personnel in 25 hospitals in the United States, the United Kingdom and Bulgaria followed doctors into rooms where patients were “coding” or “technically dead,” Parnia said.

    While doctors performed CPR, the research teams attached devices that measured oxygen and electrical activity to the dying person’s head. ... " ... We found the brains of people who are going through death have flatlined, which is what you would expect,” Parnia said.

    “But interestingly, even up to an hour into the resuscitation, we saw spikes — the emergence of brain electrical activity, the same as I have when talking or deeply concentrating,” he added.

    Those spikes included gamma, delta, theta, alpha and beta waves, according to the study.

    ... In addition, the study took the recorded brain signals and compared them with brain signals done by other studies on hallucinations, delusions and illusions and found them to be very different, he added. “We were able to conclude that the recalled experience of death is real. It occurs with death, and there’s a brain marker that we’ve identified. These electrical signals are not being produced as a trick of a dying brain, which is what a lot of critics have said.”

    ... Some experts in the field were less convinced by the study’s conclusions, which were first presented at scientific sessions in November 2022 and widely covered by the media.

    “This latest report of persistent brain waves after cardiac arrest has been blown out of proportion by the media. In fact, his team did not show any association between these brain waves and conscious activity,” said Dr. Bruce Greyson, Carlson Professor Emeritus of Psychiatry and Neurobehavioral Sciences at the University of Virginia School of Medicine in Charlottesville. “That is, those patients who had near-death experiences did not show the reported brain waves, and those who did show the reported brain waves did not report near-death experiences,” Greyson told CNN via email. ... “All (the study) has shown is that in some patients there is continued electrical activity in the head that occurs during the same period that other patients report having NDEs (near-death experiences),” Greyson said. ...

    https://us.cnn.com/2023/09/14/health...ess/index.html

    Leave a comment:


  • Jundo
    replied
    Like looking at our own baby pictures ...

    A new image from NASA's James Webb Space Telescope has captured what Earth's sun looked like when it was only a few tens of thousands of years old.

    The image of Herbig-Haro 211 (HH 211), released by NASA on Sept. 14, shows the outflow of a young star. "An infantile analogue of our Sun," NASA said in a statement.

    Located about 1,000 light-years from Earth in the constellation Perseus, HH21 has only about 8% of the Sun's mass. A Class 0 protostar, meaning the nascent star is less than 100,000 years old, "eventually will grow into a star like the Sun," Webb Space Telescope wrote on its website.

    ... Supersonic jets of gas spew from a newborn star in this new infrared image ...The bright regions are called Herbig-Haro objects, and they form when star particles collide with nearby gas and dust, forming intense shockwaves.

    And signs of our space cousins? ...

    Beyond Earth: Webb Space Telescope Detects Key Molecules on Exoplanet K2-18 b ... Planet in ‘habitable’ zone could have rare oceans and a possible sign of life, Webb data reveals

    Waters may be flowing on the surface of a colossal planet that lies about 120 light-years from Earth, according to new evidence uncovered by the James Webb Space Telescope. ... Closely orbiting the cool dwarf star K2-18, the exoplanet lies within the star’s habitable, or Goldilocks, zone and is 8.6 times as massive as Earth. An analysis of Webb’s observations found the planet has abundant methane and carbon dioxide in its atmosphere.... The presence of these carbon-bearing molecules, along with a scarcity of ammonia, could indicate an atmosphere rich with hydrogen that surrounds an ocean world, according to a NASA news release. Carbon is considered the building block of life-forms on Earth.

    ... And the latest observations of the planet also hint that a very special molecule, called dimethyl sulfide, could be present on K2-18b. On Earth, dimethyl sulfide “is only produced by life,” according to NASA. “The bulk of the DMS in Earth’s atmosphere is emitted from phytoplankton in marine environments.”

    Researchers are not outright suggesting that K2-18b is crawling with alien life. Further research is needed to confirm the presence of dimethyl sulfide, ... And even if scientists corroborate the chemical compound’s presence, that doesn’t guarantee life-forms exist there.
    The James Webb Space Telescope investigated a giant planet, K2-18b, that could be an ocean world, according to NASA. The exoplanet lies 120 light-years away from Earth.


    https://scitechdaily.com/beyond-eart...lanet-k2-18-b/
    Also ...

    Scientists Discover Amino Acid Essential for Life in Interstellar Space

    Researchers discovered evidence of the amino acid tryptophan in the interstellar material of the IC348 star system using data from the Spitzer Space Observatory. This finding suggests that protein-building amino acids are prevalent in areas where stars and planets develop, hinting at the potential for life in exoplanetary systems. ... Tryptophan is one of the 20 amino acids essential for the formation of key proteins for life on Earth ...


    https://scitechdaily.com/scientists-...stellar-space/
    While our planet becomes less friendly to life ... or, at least, our kind of life ...

    Conditions on Earth may be moving outside the ‘safe operating space’ for humanity, according to dozens of scientists

    ... The scientists analyzed nine interlinked “planetary boundaries,” which they define as thresholds the world needs to stay within to ensure a stable, livable planet. These include climate change, biodiversity, freshwater and land use, and the impact of synthetic chemicals and aerosols.

    Human activities have breached safe levels for six of these boundaries and are pushing the world outside a “safe operating space” for humanity, according to the report, published on Wednesday in the journal Science Advances.

    ... The limits are designed to be conservative, to enable society to solve the problems before reaching a “very high risk zone,” said Katherine Richardson, a professor in biological oceanography at the University of Copenhagen and a co-author on the report.

    She pointed to the unprecedented summer of extreme weather the world has just experienced at 1.2 degrees Celsius of global warming. “We didn’t think it was going to be like this at 1 degree [Celsius]” she said. “No human has experienced the conditions that we’re experiencing right now,” she added. ...

    Of the three boundaries that scientists found are still within a safe space, two of them – ocean acidification and the amount of aerosols in the atmosphere – are moving in the wrong direction.

    There is some good news, however. The ozone layer was on the wrong side of the boundary in the 1990s, Richardson said. But thanks to international cooperation to phase out ozone-depleting chemicals, it is on track to recover completely. ...

    ... But there are [also] criticisms of the model ...

    https://us.cnn.com/2023/09/13/world/...ate/index.html
    Maybe we can stick life in the freezer? ...

    Cryo Conservation – A Cool Solution to Saving Species From Extinction

    Researchers underscore the significant potential of cryobanks, which store varied genetic materials from animals at ultra-low temperatures, in safeguarding declining global animal populations. The study, conducted with the contribution of several global conservation agencies, suggests prioritizing species for future sampling and establishing a global cryobanking database to facilitate collaborative conservation efforts and possibly reintroduce threatened species to their natural habitats.

    Amidst the dire biodiversity crisis, underscored by a staggering 69% drop in global animal populations since 1970, experts are turning to an innovative solution to help avert species extinction.

    https://scitechdaily.com/cryo-conser...om-extinction/
    In the meantime ...

    Replacing 50% of meat and milk products with plant-based alternatives by 2050 can reduce agriculture and land use related greenhouse gas (GHG) emissions by 31% and halt the degradation of forest and natural land, according to new research.

    https://scitechdaily.com/plant-based...ustainability/
    But how fast are we all expanding? ... (and I don't mean the waistline) ...

    Hubble Constant Tension Mystery Deepens: Webb Space Telescope Measures the Universe’s Expansion Rate

    The “Hubble Tension” denotes the difference between the observed and expected expansion rate of the universe. The James Webb Space Telescope refines measurements previously made by the Hubble Space Telescope. Despite advancements, questions persist about the universe’s swift expansion and potential underlying cosmic phenomena.

    ... “We recently got our first Webb measurements ... What the results still do not explain is why the universe appears to be expanding so fast! ... It may indicate the presence of exotic dark energy, exotic dark matter, a revision to our understanding of gravity, or the presence of a unique particle or field. The more mundane explanation would be multiple measurement errors conspiring in the same direction (astronomers have ruled out a single error by using independent steps), so that is why it is so important to redo the measurements with greater fidelity. With Webb confirming the measurements from Hubble, the Webb measurements provide the strongest evidence yet that systematic errors in Hubble’s Cepheid photometry do not play a significant role in the present Hubble Tension. As a result, the more interesting possibilities remain on the table and the mystery of the Tension deepens.”

    https://scitechdaily.com/hubble-cons...xpansion-rate/
    Call the cable guy?

    Opinion: The Deep Space Network is in trouble

    The Deep Space Network, or DSN, is an interconnected set of three radio telescope facilities spread across the globe. These installations, located in California, Spain and Australia, are managed and operated for NASA by the Jet Propulsion Laboratory. At about 120 degrees apart in longitude, their locations were selected so that any space probe at a distance greater than 30,000 kilometers (about 18,640 miles) from Earth can be in radio contact with at least one of them.

    DSN is the main way that NASA contacts spacecraft far from Earth, including such technical marvels as the James Webb Space Telescope, the Mars 2020 Perseverance rover and even ultra-distant Voyager 1 probe — the manmade object that is currently farthest from Earth. Indeed, without the DSN, NASA’s robotic exploration of deep space would simply not be possible.

    The problem with the DSN is multifold. While it has performed brilliantly since it began operations in the 1960s and has experienced periodic upgrades, it is overtaxed and in critical need of infrastructure improvements.

    There are currently 40 missions that rely on the DSN antennas to operate, with the expectation that an additional 40 missions will be launched in the future. Given that some of the existing missions will still be functional, the demands on the network will continue to grow.https://us.cnn.com/2023/09/11/opinio...oln/index.html
    Another network ... a neural one ...

    Brain Avalanches and the Secrets of Neural Critical States Unveiled

    New research shows that when neurons are given information about the changing world around them (task-related sensory input) it changes how they behave, putting them on edge so that tiny inputs can then set off ‘avalanches’ of brain activity, supporting a theory known as the critical brain hypothesis. ... This fine-balanced state is known as a “neural critical” state, and lies between two extremes – the runaway excitation seen in disorders such as epilepsy, and a coma state where signals stall. ... “The results are astonishing, way beyond what we thought we would achieve.” ...

    https://scitechdaily.com/brain-avala...ates-unveiled/
    Brain pain ...

    New Research Uncovers That Everyone’s Brain Has a Unique “Pain Fingerprint”

    New research discovered individual variability in gamma oscillations in the brain, previously thought to represent pain perception. This study found these brain waves are consistent within individuals but vary widely across individuals, leading the researchers to suggest a need for revisiting past research methodologies.

    ... Interestingly, some recorded feeling pain and having no gamma response, whilst others had a large response. At this stage, it is not known why there is such variation – but it is hoped this will be a springboard for future research.

    https://scitechdaily.com/new-researc...n-fingerprint/
    Autoimmune hope ...

    New Vaccine Can Completely Reverse Autoimmune Diseases Like Multiple Sclerosis, Type 1 Diabetes, and Crohn’s Disease

    Researchers at the University of Chicago have developed an “inverse vaccine” that can reverse autoimmune diseases such as multiple sclerosis and type 1 diabetes without suppressing the overall immune system. The vaccine erases the immune system’s harmful memory of specific molecules, halting the autoimmune response where the immune system wrongly attacks healthy tissues.

    https://scitechdaily.com/new-vaccine...rohns-disease/
    Still so many mysteries within us ...

    The “Unknome”: A Database of Human Genes We Know Almost Nothing About

    Researchers from the UK have developed a publicly accessible database, the “unknome”, which lists thousands of understudied proteins encoded by human genes. By assigning a “knownness” score to each protein based on existing scientific knowledge, the platform aids researchers in exploring these proteins’ functions, many of which play critical roles in cellular processes.

    ... the risks of ignoring these proteins are significant, the authors argue, since it is likely that some, perhaps many, play important roles in critical cell processes, and may both provide insight and targets for therapeutic intervention. ...

    https://scitechdaily.com/the-unknome...nothing-about/
    This gave me a charge ...

    Fully Charged in Just 6 Minutes – Groundbreaking Technique Could Revolutionize EV Charging

    Electric vehicles traditionally take hours to charge, but a new anode material developed by Professor Won Bae Kim’s team at POSTECH can reduce this time to just six minutes. This advancement is due to the use of manganese ferrites nanosheets, synthesized through a unique method, improving battery capacity and charging speed.



    ALSO:

    Researchers at Oak Ridge National Laboratory have developed a lithium-ion battery material that can recharge 80% in 10 minutes and maintain this for 1,500 cycles. The team achieved this by creating a new electrolyte formulation that enhances ion flow and withstands high currents during rapid charging.


    AI steps up ...

    New Study: AI Chatbots Surpass the Average Human in Creativity

    A recent study published in the journal Scientific Reports suggests that large language model (LLM) AI chatbots might excel beyond the average human in creative tasks, like brainstorming alternate uses for common items – a reflection of divergent thinking. However, individuals who scored the highest in these tasks still surpassed the top-performing chatbot results.

    https://scitechdaily.com/new-study-a...oogle_vignette
    'Like a teacher there 24/7': ChatGPT tool supports English education at Japan univ.

    Ritsumeikan University has been experimentally introducing an English learning support tool combining ChatGPT and machine translation functions in some of its English classes since this spring ... "Transable" automatically translates Japanese into English, and at the same time checks the grammar of the translated English sentences. It can also back-translate English texts into Japanese and on the same screen check whether the English sentences have been created as intended.

    Furthermore, by incorporating ChatGPT, users can ask questions and demand things in addition to receiving an explanation as to why the translated English text is correct. For example, if one asks for the use of a different phrase, multiple English expressions will be suggested. Moreover, users can have ChatGPT evaluate the quality of English sentences they have created on their own and have it point out any mistakes.

    Kohei Sugiyama, a doctoral student at the university's Graduate School of Science and Engineering who developed the tool, explained, "It's like having an English teacher who is always there for you, 24/7."

    https://mainichi.jp/english/articles...0m/0na/029000c
    And ... wow, just wow ...

    Digital clones, Vocaloids popular in Japan, but may get lost in translation elsewhere

    Kazutaka Yonekura dreams of a world where everyone will have their very own digital "clone" -- an online avatar that could take on some of our work and daily tasks, such as appearing in Zoom meetings in our place.

    Yonekura, chief executive of Tokyo startup Alt Inc., believes it could make our lives easier and more efficient.

    His company is developing a digital double, an animated image that looks and talks just like its owner. The digital clone can be used, for example, by a recruiter to carry out preliminary job interviews, or by a physician to screen patients ahead of checkups.

    "This liberates you from all the routine (tasks) that you must do tomorrow, the day after tomorrow and the day after that," he told The Associated Press as he showed off his double -- a thumbnail video image of Yonekura on the computer screen, with a synthesized version of his voice.

    ... For now, having a digital double is expensive. Each Alt clone costs about 20 million yen ($140,000), so it will likely take some time before there's a clone for everyone.

    In creating a digital double, information about a person is skimmed off social media sites and publicly available records in a massive data collection effort, and stored in the software. The data is constantly updated, keeping in synch with the owner's changing habits and tastes.

    Yonekura believes a digital clone could pave the way for a society where people can focus on being creative and waste less time on tedious interactions. ...

    https://mainichi.jp/english/articles...0m/0na/023000c

    Gassho, J

    stlah

    Leave a comment:


  • Jundo
    replied
    The Diamond Sutra:

    So you should view this fleeting world --
    A star at dawn, a bubble in a stream ...


    Vast Bubble of Galaxies Discovered – Believed To Be a Remnant From the Universe’s Inception

    Astronomers have identified an immense bubble, Hoʻoleilana, 820 million light years away. This structure, believed to be a remnant from the universe’s inception and larger than predicted, offers valuable insights into galaxy evolution and the universe’s expansion dynamics. ... In the well-established Big Bang theory, during the first 400,000 years, the universe was a cauldron of hot plasma similar to the interior of the Sun. Within a plasma, electrons were separated from the atomic nuclei. During this period, regions with slightly higher density began to collapse under gravity, even as the intense bath of radiation attempted to push matter apart. This struggle between gravity and radiation made the plasma oscillate or ripple and spread outward.

    The largest ripples in the early universe depended on the distance a sound wave could travel. Set by the speed of sound in the plasma, this distance was almost 500 million light years, and was fixed once the universe cooled and stopped being a plasma, leaving vast three-dimensional ripples. Throughout the eons, galaxies formed at the density peaks, in enormous bubble-like structures. Patterns in the distribution of galaxies, properly discerned, could reveal the properties of these ancient messengers.

    ... Tests with simulations have demonstrated that the shell structure identified as Hoʻoleilana has less than a 1% probability of being a statistical accident. ...

    BELOW: The red region (left) shows the shell enclosed by the Baryon Acoustic Oscillation, with individual galaxies depicted as luminous tiny specks. The blue filaments show the greater Cosmic Web, with previously known features like Laniākea highlighted.


    The new findings mention these massive structures are predicted by the Big Bang theory, as the result of 3D ripples found in the material of the early universe, known as Baryon Acoustic Oscillations (BAO).


    https://scitechdaily.com/vast-bubble...ses-inception/
    The Black Holes are there ... just not so many rapidly growing ones ...

    What Happened to All the Supermassive Black Holes? Astronomers Surprised by Webb Data

    A research study using the James Webb Space Telescope has found that active galactic nuclei, supermassive black holes that grow rapidly [AGN], are less common than previously thought. ... The findings, made with the JWST’s Mid-Infrared Instrument (MIRI), suggest our universe may be a bit more stable than was supposed. ... While every galaxy features a supermassive black hole at the middle, AGN are more spectacular upheavals actively drawing in gases and showing a luminosity absent from typical black holes. ... “The study’s findings suggest that these black holes are not growing rapidly, absorbing limited material, and perhaps not significantly impacting their host galaxies,” she said. “This discovery opens up a whole new perspective on black-hole growth since our current understanding is largely based on the most massive black holes in the biggest galaxies, which have significant effects on their hosts, but the smaller black holes in these galaxies likely do not.” ...

    ... “Our [Milky Way] black hole seems quite uneventful, not displaying much activity,” she said.

    https://scitechdaily.com/what-happen...-by-webb-data/
    But them black holes don't fool around if they catch you ...

    Ripped Apart: A Gigantic Black Hole Destroys a Massive Star

    Astronomers, using the Chandra X-ray Observatory and XMM-Newton, meticulously studied the remains of a star obliterated by a massive black hole. This event, ASASSN-14li, offers unprecedented insights due to its proximity to Earth. The research reveals the star to be one of the most massive ever consumed by a black hole.

    The universe's eyelashes??

    Cosmic Keyhole: Webb Reveals Breathtaking New Structures Within Iconic Supernova

    Webb’s NIRCam (Near-Infrared Camera) captured this detailed image of SN 1987A (Supernova 1987A), located 168,000 light-years away in the Large Magellanic Cloud, which has been annotated to highlight key structures. At the center, material ejected from the supernova forms a keyhole shape. Just to its left and right are faint crescents newly discovered by Webb. Beyond them an equatorial ring, formed from material ejected tens of thousands of years before the supernova explosion, contains bright hot spots. Exterior to that is diffuse emission and two faint outer rings.



    A new look at our own star ...

    Uncharted Solar Realms: Camera “Hack” Lets Solar Orbiter Peer Deeper Into Sun’s Atmosphere

    Scientists have used Solar Orbiter’s EUI camera in a new mode of operation to record part of the Sun’s atmosphere at extreme ultraviolet wavelengths that has been almost impossible to image until now. ...

    BELOW: This movie shows an ultraviolet image of the Sun’s corona taken using the EUI occulter. An ultraviolet image of the Sun’s disc has been superimposed in the middle, in the area left blank by the occulter.


    https://scitechdaily.com/uncharted-s...ns-atmosphere/
    This is important to any future colonization ... SUCCESSFUL MANUFACTURE OF OXYGEN ON MARS!

    The first experiment to produce oxygen on another planet has come to an end on Mars after exceeding NASA’s initial goals and demonstrating capabilities that could help future astronauts explore the red planet.

    The microwave-size device called MOXIE, or Mars Oxygen In-Situ Resource Utilization Experiment, is on the Perseverance rover.

    The experiment kicked off more than two years ago, a few months after the rover landed on Mars. Since then, MOXIE has generated 122 grams of oxygen, equal to what a small dog breathes in 10 hours, according to NASA. The instrument works by converting some of Mars’ plentiful carbon dioxide into oxygen. ... During the peak of its efficiency, MOXIE produced 12 grams of oxygen an hour at 98% purity or better, which is twice as much as NASA’s goals for the instrument. ... Bigger and better versions of something such as MOXIE in the future could supply life support systems with breathable air and convert and store oxygen needed for rocket fuel used to launch on a return trip to Earth.

    BELOW: Engineers installed MOXIE inside the chassis of the Perseverance rover in 2019.


    The first experiment to create oxygen on another planet has reached a successful end on Mars after demonstrating technology that could help humans live on the red planet.

    But Nasa's moon rockets cost too much ... with budgets reaching to the Moon ...

    NASA’s mega moon Artemis rocket is ‘unaffordable,’ according to accountability report

    https://us.cnn.com/2023/09/07/world/...scn/index.html
    Maybe an aspect of life's early chemistry ...

    Scientists Unearth Primordial Photoredox Catalyst

    Researchers have demonstrated that a solid formed from ammonia and methane plasma can use sunlight to catalyze amine-to-imine conversions, a process potentially pivotal in the formation of early biomolecules. The study suggests the primordial atmosphere may have provided the necessary catalysts for such conversions, supporting the evolution of early RNA molecules.

    https://scitechdaily.com/scientists-...oogle_vignette
    Climate tipping points have changed life (for better and ... worse) ... and it may happen again ...

    Over the past 66 million years, two major climate events have shaped the climate system, dividing the period into two distinct climate eras.

    ... An analysis of the hierarchy of tipping points indicates that over the past 66 million years, two significant occurrences laid the foundation for subsequent climate tipping and, specifically, the evolution of the climate system. The authors propose that if the current anthropogenic climate change results in total deglaciation, it will impact the development of Earth’s climate on a geological timescale.

    ... The first event was the Chicxulub meteor impact in Mexico which killed off the large dinosaurs approximately 65,5 million years ago. This catastrophe marked the beginning of a very warm period with high levels of CO2. For the following 30 million years this regime dictated which climatic changes were possible and kept it within the regime of hot and warm climates.

    The second crucial event was the tipping point associated with the glaciation of the Southern hemisphere 34 million years ago when the Antarctic continent was isolated at the South Pole due to plate tectonics. The forming of the large ice sheet led to the glaciation of the North as well and marked the beginning of a considerably colder type of climate on Earth, again dictating the scope of future climate changes. ... The analysis additionally suggests that our current global climate system still belongs to the latter climate regime and still depends on the existence of the gigantic ice bodies built within the Coolhouse/Icehouse era.

    In the event that the ice sheets should not withstand anthropogenic global warming, the deglaciation will therefore represent a landmark tipping point similar to the two that have dominated Earth’s history leading to a new unknown climate landscape.

    ”The ice sheets are key components in the present climate system. But they are very sensitive. They presently experience a negative mass balance, and there are numerous reports of evidence of melting under the impact of the current climate warming, translating a trend towards a potential tipping point that could accelerate the disappearance at least of Greenland and West Antarctica, with serious repercussions for our societies” says Denis-Didier Rousseau.


    And then, we almost got wiped out before ... except not our ancestors, at least two of the 1280 (proven by your looking in the mirror) ...

    Scientists say they have pinpointed the moment humanity almost went extinct

    Ancient humanity was almost wiped out about 900,000 years ago when the global population dwindled to around 1,280 reproducing individuals, according to a new study. What’s more, the population of early human ancestors stayed this small for about 117,000 years.

    The analysis, published August 31 in the journal Science, is based on a new computer model developed by a group of scientists based in China, Italy and the United States. The statistical method used genetic information from 3,154 present-day human genomes.

    Around 98.7% of human ancestors were lost, according to the study. The researchers argue that the population crash correlates with a gap in the fossil record, possibly leading to the emergence of a new hominin species that was a common ancestor of modern humans, or Homo sapiens, and Neanderthals.

    “The novel finding opens a new field in human evolution because it evokes many questions, such as the places where these individuals lived, how they overcame the catastrophic climate changes, and whether natural selection during the bottleneck has accelerated the evolution of human brain,” said senior author Yi-Hsuan Pan, an evolutionary and functional genomicist at East China Normal University, in a statement.

    The population bottleneck coincided with dramatic changes in climate during what’s known as the mid-Pleistocene transition, the research team suggested. Glacial periods became longer and more intense, leading to a drop in temperature and very dry climatic conditions.

    Moreover, the scientists suggested that the control of fire, as well as the climate shifting to be more hospitable for human life, could have contributed to a later rapid population increase around 813,000 years ago.


    The earliest evidence of the use of fire to cook food dates from 780,000 years ago in what is now modern-day Israel, the authors noted.

    While ancient DNA has revolutionized our understanding about past populations, the oldest DNA from a human species dates to around 400,000 years ago.

    The computer model uses the vast amount of information contained in modern human genomes about genetic variation over time to infer the size of populations at specific points in the past. The team used genetic sequences from 10 African and 40 non-African populations.

    ... [However] two researchers, who were not involved in the study, said ... the fossil record, while sparse, did show that early human species lived in and outside Africa about 813,000 to 930,000 years ago — during the period of proposed population collapse, with fossils from that era found in what’s now China, Kenya, Ethiopia, Italy, Spain and the United Kingdom. “Whatever caused the proposed bottleneck may have been limited in its effects on human populations outside the Homo sapiens lineage or its effects were short-lived,” the two researchers said in the commentary. ...

    The population of early humans dwindled to around 1,280 individuals during a time of dramatic climate change and remained that small for about 117,000 years, the study said.


    and

    https://scitechdaily.com/humanitys-n...-wiped-us-out/
    Speaking of Neanderthals ... who maybe could not speak ...

    Similar to contemporary humans, Neanderthals crafted and utilized bone tools for their daily needs.

    Were anatomically modern humans the only ones who knew how to turn bone into tools? A new discovery at the Chez-Pinaud-Jonzac Neanderthal site by an international research team puts this question to rest. Published in the journal PLOS ONE, the findings illuminate a little known aspect of Neanderthal technology.

    Starting from 45,000 years ago, anatomically modern humans began to appear in Western Europe, eventually replacing the last remaining Neanderthal communities. This period also marked significant shifts in material culture, notably the introduction of a wide array of bone artifacts—ranging from hunting tools and decorative ornaments to intricately carved figurines—by modern human groups. ... Their absence from Neanderthal sites has led to the assumption that these groups did not produce bone tools and implements, sometimes inferred to reflect cognitive differences between the two populations. Since Neanderthals did not know how to process this raw material, they were limited to picking up bone fragments amongst butchery remains, using them uniquely as retouchers for shaping flint tools.

    New excavations at the Neanderthal site of Chez-Pinaud-Jonzac (Charente-Maritime), carried out by an international team since 2019, have made it possible to reconsider this assumption. Current studies have shown that bone tools are as numerous as flint ones. Moreover, their diversity provides evidence for a genuine industry that consists not only of retouchers but also of cutting tools, scrapers, chisels, and smoothers, used for various activities and on multiple materials. ... The discovery of a bone industry at Chez-Pinaud-Jonzac is consistent with evidence uncovered a few years earlier by the same team at the Neanderthal site of Chagyrskaya, in the Siberian Altai. These two sites, located on either side of the Neanderthal range, testify to the fact that, like modern humans, Neanderthal made and used bone tools for their daily needs.

    BELOW: Multi-functional bone tool, retouched on one of its edges, used as a retoucher and chisel.


    https://scitechdaily.com/challenging...-neanderthals/
    But maybe wrong about Neanderthals, burial and flowers ... although they did tend to their dead ones it seems ...

    A ‘flower burial’ unearthed in 1960 reshaped the study of Neanderthals. A new discovery calls it into question

    ... Over the years, scientists found further evidence of Neanderthals’ intelligence and complexity, including art, string, and tools. However, elements of the flower burial theory didn’t seem to add up. ... The new study published in the Journal of Archaeological Science puts forth an alternative hypothesis: Instead of arriving to the cave via funerary bouquets, the pollen might have hitched a ride with cave-dwelling pollinators [such as bees] ...

    [BUT] ... While Hunt and his colleagues’ work suggests that the flower burial hypothesis is incorrect, the recent work on Shanidar Cave Neanderthals supports the underlying message of the old theory: that Neanderthals treated their dead with care. ... The cave itself seems to have carried some sort of meaning, since the skeletons in it were interred separately, years apart. “As far as I can see, they must have had stories in their groups about, ‘Well, this is what we did with Grandma, and now that young Joe has died, perhaps we should put him in the same place,’” Hunt said. The skeletons in the cave share common orientations and positioning, indicating that there may have been some meaning associated with how they were laid to rest. Shanidar 4 and Shanidar Z, a more recent skeleton discovery published in 2020, were found near splintered pieces of wood; Hunt said he wonders if those might have been from branches laid over the bodies to protect them.

    In particular, Hunt said Shanidar Z was positioned as if she were sleeping.

    “There was tenderness there. They cared for that individual, quite clearly,” he said. “Because why else would you do it?”

    https://us.cnn.com/2023/09/06/world/...scn/index.html
    Of course, the big changes came from the brain ...

    Scientists Unveil Unprecedented “Live” View Into the Brain’s Complexity

    Researchers have developed a new imaging and virtual reconstruction technology named LIONESS, which offers high-resolution imaging of live brain tissue, visualizing it in real-time 3D nanoscale detail. ... LIONESS is a pipeline to image, reconstruct, and analyze live brain tissue with a comprehensiveness and spatial resolution not possible until now. ...

    BELOW: LIONESS delineates the complexity of dense brain tissue. a: Complex neuronal environment b: LIONESS can image and reconstruct the sample in a way that clarifies many dynamic structures and functions in live brain tissue.


    It was there all along, we just didn't know it ... in our brains ...

    Shaking the Foundations of Neuroscience: The Astonishing Discovery of a New Type of Brain Cell

    Neuroscience is in great upheaval. The two major families of cells that make up the brain, neurons and glial cells, secretly hid a hybrid cell, halfway between these two categories. ... This cell can release neurotransmitters and may influence conditions like epilepsy and memory consolidation, offering promising paths for neuroscientific research and potential treatments. ...

    For as long as Neuroscience has existed, it has been recognized that the brain works primarily thanks to the neurons and their ability to rapidly elaborate and transmit information through their networks. To support them in this task, glial cells perform a series of structural, energetic, and immune functions, as well as stabilize physiological constants.

    Some of these glial cells, known as astrocytes, intimately surround synapses, the points of contact where neurotransmitters are released to transmit information between neurons. This is why neuroscientists have long suggested that astrocytes may have an active role in synaptic transmission and participate in information processing. However, the studies conducted to date to demonstrate this have suffered from conflicting results and have not reached a definitive scientific consensus yet. By identifying a new cell type with the characteristics of an astrocyte and expressing the molecular machinery necessary for synaptic transmission, neuroscientists from the Department of Basic Neurosciences of the Faculty of Biology and Medicine of the University of Lausanne (UNIL) and the Wyss Center for Bio and Neuroengineering in Geneva put an end to years of controversy.

    https://scitechdaily.com/shaking-the...of-brain-cell/
    ... and swirling spirals ... makes my head spin ...

    The Missing Link in Cognitive Processing? Scientists Discover Swirling Spirals in the Brain

    Scientists have discovered that human brain signals form swirling spirals on the outer layer of neural tissue, which play a crucial role in organizing brain activity and cognitive processes. This discovery, based on fMRI scans, could advance our understanding of brain dynamics, potentially leading to better computational models and insights into brain diseases like dementia.

    ...
    “These spiral patterns exhibit intricate and complex dynamics, moving across the brain’s surface while rotating around central points known as phase singularities

    “Much like vortices act in turbulence, the spirals engage in intricate interactions, playing a crucial role in organizing the brain’s complex activities.

    “The intricate interactions among multiple co-existing spirals could allow neural computations to be conducted in a distributed and parallel manner, leading to remarkable computational efficiency.” ...

    ... The cortex of the brain, also known as the cerebral cortex, is the outermost layer of the brain that is responsible for many complex cognitive functions, including perception, memory, attention, language, and consciousness.

    “One key characteristic of these brain spirals is that they often emerge at the boundaries that separate different functional networks in the brain,” Mr. Xu said. ... “Through their rotational motion, they effectively coordinate the flow of activity between these networks." ...


    https://scitechdaily.com/the-missing...oogle_vignette
    Learning ebbs and flows ... makes me dopey ...

    “Ebb and Flow” Brain Mechanism Discovered – Study Challenges Traditional Views on Role of Dopamine in Learning

    New research reveals that learning in the brain occurs not just when there are external rewards like food or money, but also naturally through the constant ebb and flow of dopamine and acetylcholine. The researchers found that this hormonal balancing act is ongoing and independent of rewards, potentially offering new insights into neuropsychiatric conditions.

    https://scitechdaily.com/ebb-and-flo...e-in-learning/
    Maybe a little jolt can help the process ...

    Electrifying Learning: How Brain Stimulation Can Improve Math Learning

    Electrical noise stimulation targeted at a specific brain area can enhance math learning in individuals who find the subject challenging, reveals a recent study conducted by researchers from the Universities of Surrey and Oxford, Loughborough University, and Radboud University in The Netherlands.

    The unique study explored the influence of neurostimulation on the learning process. Although there is an increasing interest in this non-invasive method, there is limited understanding of the induced neurophysiological alterations and their implications on learning.

    https://scitechdaily.com/electrifyin...math-learning/
    The Bees get an A+ ... we get a B ... AI might someday beat us all ...

    Researchers Discover That Bees Can Make Decisions Better and Faster Than We Do

    ... “Decision-making is at the core of cognition,” says Professor Barron. “It’s the result of an evaluation of possible outcomes, and animal lives are full of decisions. A honey bee has a brain smaller than a sesame seed. And yet she can make decisions faster and more accurately than we can. A robot programmed to do a bee’s job would need the backup of a supercomputer.

    ... The team then built a computer model from first principles aiming to replicate the bees’ decision-making process. They found the structure of their computer model looked very similar to the physical layout of a bee brain. “Our study has demonstrated complex autonomous decision-making with minimal neural circuitry,” says Professor Marshall. ... AI researchers can learn much from insects and other ‘simple’ animals. Millions of years of evolution have led to incredibly efficient brains with very low power requirements. The future of AI in the industry will be inspired by biology, says Professor Marshall, who co-founded Opteran, a company that reverse-engineers insect brain algorithms to enable machines to move autonomously, like nature. ...

    https://scitechdaily.com/researchers...er-than-we-do/
    Speaking of the first brain, second thoughts on the second brain ...

    Fundamental Biology Overturned: New Discovery Challenges Long-Held Views on “The Second Brain”

    ... The entire digestive tract is lined by the enteric nervous system (ENS), a vast network of millions of neurons and glial cells—the two primary cell types also found in the central nervous system. While often called the second brain, the ENS not only generates the same neurotransmitters but actually predates the evolution of the central nervous system in the brain. ... Researchers have discovered that ENS development continues after birth and includes neurons derived from mesoderm, challenging long-held scientific beliefs and opening avenues for potential new treatments for aging and gastrointestinal diseases. ...

    https://scitechdaily.com/fundamental...-second-brain/
    I should program AI just to write these science posts each week ...

    ChatGPT vs. Humans: Even Linguistic Experts Can’t Tell Who Wrote What

    According to a recent study co-authored by an assistant professor from the University of South Florida, even linguistics experts struggle to discern between writings produced by artificial intelligence and those written by humans. ... “We thought if anybody is going to be able to identify human-produced writing, it should be people in linguistics who’ve spent their careers studying patterns in language and other aspects of human communication,” said Matthew Kessler, a scholar in the USF the Department of World Languages. ... Kessler tasked 72 experts in linguistics with reviewing a variety of research abstracts to determine whether they were written by AI or humans.

    Each expert was asked to examine four writing samples. None correctly identified all four, while 13 percent got them all wrong.

    ... The silver lining for human authors [FOR NOW] lies in longer forms of writing. “For longer texts, AI has been known to hallucinate and make up content, making it easier to identify that it was generated by AI,” Kessler said. ...

    https://scitechdaily.com/chatgpt-vs-...oogle_vignette
    Hard to detect this way too ...

    Stanford Researchers Expose Flaws in Text Detectors

    ... Researchers have found that GPT detectors, used to identify if text is AI-generated, often falsely label articles written by non-native English speakers as AI-created. This unreliability poses risks in academic and professional settings, including job applications and student assignments. ... The researchers warn that the unreliable performance of these AI text-detection programs could adversely affect many individuals, including students and job applicants.

    “Our current recommendation is that we should be extremely careful about and maybe try to avoid using these detectors as much as possible,” says senior author James Zou, of Stanford University. “It can have significant consequences if these detectors are used to review things like job applications, college entrance essays, or high school assignments.”

    ... Zou explains that the algorithms of these detectors work by evaluating text perplexity, which is how surprising the word choice is in an essay. “If you use common English words, the detectors will give a low perplexity score, meaning my essay is likely to be flagged as AI-generated. If you use complex and fancier words, then it’s more likely to be classified as human written by the algorithms,” he says. This is because large language models like ChatGPT are trained to generate text with low perplexity to better simulate how an average human talks, Zou adds. As a result, simpler word choices adopted by non-native English writers would make them more vulnerable to being tagged as using AI. ...

    A big AI gamble ...

    Robots are pouring drinks in Vegas. As AI grows, the city's workers brace for change

    Walk any direction in Las Vegas and it's easy to find machines doing human work.

    Check-in kiosks have replaced people at the front desk of hotels. Text-bots now make restaurant recommendations instead of a concierge. Robots can serve food, and behind the bar, machines are pouring out drinks.

    Automation and technology replacing jobs has long been a conversation in Nevada's most populated city. Studies show that between 38% to 65% of jobs there could be automated by 2035.

    With the use of artificial intelligence on the rise, the economy of this city --which relies on tourism and hospitality — is at an inflection point, as companies look to technology to reduce labor costs. ...

    ... "The question is, how do you factor in and how do you adapt your economic development strategy, your community strategy, your resiliency strategy to accommodate a world where certain jobs no longer exist?" he said. Restrepo said he believes the city has to diversify its economy to be less reliant on tourism and hospitality. "We need to move ... to those occupations that are more highly skilled, that are not easily replaced by AI and that provide a greater level of balance and resilience so we're not so hard-hit," Restrepo said.

    ... The Culinary Union is prepared to strike over AI ...

    ... Bergman and other service workers told NPR there are some human jobs that technology can't eliminate. Machines don't have the same human touch and cannot provide the same experience, they said — and often times, the machines add more work.

    "We have a lot of guests that are regular guests, and they come for the personal interaction. They don't come for the technology," said Holly Lang, a cocktail waitress at the MGM Grand. "There's some things you can't replace." ...

    ... It's not just service workers who will be affected ...

    Artificial intelligence won't just impact lower-wage jobs. Technology like ChatGPT, which is a form of generative AI, will impact white collar jobs, too, in fields like accounting and data entry. ...

    https://www.npr.org/2023/09/04/11971...ace-for-change
    Oh my ...

    Ads for AI sex workers are flooding Instagram and TikTok

    Apps promising AI-generated sexual images and companionship are running hundreds of ads on social media. Human sex workers are often banned.

    Facebook, Instagram and TikTok have tried to keep a tight lid on sexualized content in recent years, banning nudity outright in almost all cases, kicking off sex workers and even cracking down on some artists and educators who speak frankly about sexual health and safety.

    But a new kind of sexualized content has lately been getting through their moderation systems: ads for scantily clad and dirty-talking chatbots, powered by what their creators say is artificial intelligence.

    Dozens of tech startups have been running explicit advertisements on TikTok, Instagram and Facebook in recent months for apps that promote not-safe-for-work experiences. The ads promise “NSFW pics,” custom pinup girls and chats with “no censoring,” and many of them feature digitally created potential “girlfriends” with large breasts and tight clothing.

    Some ads use memes that include popular children’s TV characters, such as SpongeBob SquarePants, Bart Simpson or Cookie Monster, to promote apps with which people can create “NSFW pics.” Others feature digitally created girls who appear to be teenagers or younger, sometimes in the style of anime. ...


    Apps promising AI-generated sexual images and companionship are running hundreds of ads on social media. Human sex workers are often banned.

    Another kind of AI attraction ...

    Magnet Magic: How AI Is Revolutionizing Material Discovery

    A team of researchers from the U.S. Department of Energy’s Ames National Laboratory developed a new machine learning model for discovering critical-element-free permanent magnet materials. The model predicts the Curie temperature of new material combinations. It is an important first step in using artificial intelligence to predict new permanent magnet materials. This model adds to the team’s recently developed capability for discovering thermodynamically stable rare earth materials. High-performance magnets are essential for technologies such as wind energy, data storage, electric vehicles, and magnetic refrigeration. These magnets contain critical materials such as cobalt and rare earth elements like Neodymium and Dysprosium. These materials are in high demand but have limited availability. This situation is motivating researchers to find ways to design new magnetic materials with reduced critical materials.

    https://scitechdaily.com/magnet-magi...ial-discovery/
    Blending body and machine ...

    Paving the Way for Tiny Devices Integrated Into Human Tissues – Scientists Develop New “Droplet” Battery

    Researchers from the University of Oxford have achieved a major advancement toward realizing miniature bio-integrated devices, capable of directly stimulating cells. Their findings were recently published in the journal Nature.

    Small bio-integrated devices that can interact with and stimulate cells could have important therapeutic applications, such as targeted drug delivery and promoting faster wound recovery. A major obstacle, however, has been providing an efficient microscale power source for these devices, a challenge that has remained unsolved. ... Inspired by how electric eels generate electricity, the device uses internal ion gradients to generate energy. ...

    ... ‘This work addresses the important question of how stimulation produced by soft, biocompatible devices can be coupled with living cells. The potential impact on devices including bio-hybrid interfaces, implants, and microrobots is substantial.’ ...


    And machines based on bodies ...

    DNA Chips: The Billion Gigabyte Storage Solution of Tomorrow

    The hereditary molecule DNA is renowned for its ability to store vast amounts of information over long periods of time in an incredibly small space. For a good ten years, scientists have therefore been pursuing the goal of developing DNA chips for computer technology, especially for the long-term archiving of data. Such chips would be superior to conventional silicon-based chips in terms of storage density, longevity, and sustainability.

    ... “The fact that digital DNA data storage with high capacity and a long lifespan is feasible has been demonstrated several times in recent years,” says Professor Thomas Dandekar, head of the Chair of Bioinformatics at Julius-Maximilians-Universität (JMU) Würzburg. “But the storage costs are high, close to 400,000 US dollars per megabyte, and the information stored in the DNA can only be retrieved slowly. It takes hours to days, depending on the amount of data.” These challenges must be overcome to make DNA data storage more applicable and marketable. Suitable tools for this are light-controlled enzymes and protein network design software. Thomas Dandekar and his chair team members Aman Akash and Elena Bencurova discuss this in a recent review in the journal Trends in Biotechnology.

    Dandekar’s team is convinced that DNA has a future as a data store. In the journal, the JMU researchers show how a combination of molecular biology, nanotechnology, novel polymers, electronics, and automation, coupled with systematic development, could make DNA data storage useful for everyday use possible in a few years.

    https://scitechdaily.com/dna-chips-t...oogle_vignette
    This is potential good news ...

    Scientists Develop New Cancer Therapy That Stops Tumor Growth in Its Tracks

    Researchers from Purdue University have developed a novel cancer treatment that deceives cancer cells into absorbing a snippet of RNA that naturally blocks cell division. A study recently published in Oncogene reveals that over a 21-day period, tumors subjected to this treatment remained unchanged in size, whereas untreated tumors grew threefold.

    Cancer can begin almost anywhere in the human body. It is characterized by cells that divide uncontrollably and that may be able to ignore signals to die or stop dividing, and even evade the immune system. The therapy, tested in mouse models, combines a delivery system that targets cancer cells with a specially modified version of microRNA-34a, a molecule that acts “like the brakes on a car,” slowing or stopping cell division, said Andrea Kasinski, lead author and the William and Patty Miller Associate Professor of biological sciences at Purdue Universit ... In healthy cells, microRNA-34a is abundant, but its presence is dramatically reduced in many cancer cells. ...

    https://scitechdaily.com/scientists-...oogle_vignette
    A kidney purse made from a sow's ear? ... a man inside a pig? ...

    Scientists take ‘pioneering steps’ toward growing human kidneys in pigs


    Scientists have grown kidneys containing mostly human cells inside pig embryos, an important step toward growing kidneys and potentially other human organs that could be used for transplants in people.

    The technique, described in a new study published Thursday in the scientific journal Cell Stem Cell, entails altering the genetic makeup of pig embryos and then injecting human cells that will go on to make a kidney inside the animals. The researchers involved said it’s the first time scientists have been able to grow a solid humanized organ inside another species. The embryos, when implanted in surrogate pig mothers, began to grow kidneys containing mostly human cells that had a normal structure after 28 days of development, according to the study.

    ... The team is also working to generate other human organs in pig embryos, including the heart and pancreas. ...

    ... Ethical considerations surround this type of research. These include animal welfare and concerns that human cells could become involved in not only forming the kidney but other tissues inside the pig, such as its brain ... “It is very important to note that there was very little contribution of human cells to other lineages apart from the kidney. We saw very few human cells in the central nervous system and none in the germline (reproductive cells).”

    BELOW: Humanized kidney cells inside a pig embryo are shown in red

    [ATTACH=CONFIG]8819[/ATTACH]

    https://us.cnn.com/2023/09/07/health...scn/index.html
    Kidneys in space! ...

    Biotech Research on Station: Exploring DNA and Organ Printing in Space

    ... Moghbeli then assisted JAXA (Japan Aerospace Exploration Agency) astronaut Satoshi Furukawa as he replaced components on the BioFabrication Facility (BFF). The 3D biological printer is testing the printing of organ-like tissues in microgravity with an eye to manufacturing whole human organs in space in the future. ...

    https://scitechdaily.com/biotech-res...oogle_vignette
    This is just fascinating ... what we do with our time each day ... although, of course, depends on where we live and who we are ...

    But sure doesn't sound like my day!!! Work for only 2.6 hours???

    Researchers conducted a comprehensive study to understand how people across the globe allocate their time.

    ... The researchers found that the single largest chunk of time goes towards activities that are human-centered – a little more than 9 hours. Sleep or being in bed accounts for an additional 9 hours (the global estimate includes youth who tend to sleep longer hours). Of the remaining 6 hours, growing and collecting our food, preparing it, commuting and moving around, and allocational tasks (such as trade, finance, sales, law, governance, policing) each occupy around 1 hour. Waste management accounted for just 1 minute of the global day, in stark contrast to the 45 minutes spent tidying and maintaining our dwellings. All infrastructure and building construction is accomplished in about 15 minutes. ... Surprisingly, time spent on activities like meals, daily travel, hygiene and grooming, and food preparation doesn’t change in a systematic way with the material wealth of a population. In contrast, the time spent growing and collecting food varied strongly with wealth, from over 1 hour in low-income countries to less than 5 minutes in high-income countries. ...

    ... Just a tenth of the day is given over to economic activities
    Since the study includes both economic and non-economic activities, a portion of the total time in each of the categories described above represents people engaged in economic activity – e.g., doctors and nurses, cooks and agricultural laborers, etc.

    The team estimated that the entire global economy occupies around 2.6 hours of the average human day. This economic activity is dominated by agriculture and livestock production, followed by allocational activities like trade, finance and law, and manufacturing. While the total of 2.6 hours may seem small, for the two-thirds of the world’s working-age population (ages 15-64) who make up the labor force this equates to about a 40-hour work week. ...


    https://scitechdaily.com/190-billion...oogle_vignette
    Need more time for Zazen there!

    Gassho, J

    stlah
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    The mysterious phenomenon that Einstein once described as “spooky action at a distance” was seen as a wavefunction between two entangled photons. 


    Quantum entanglement visualized for the first time ever.

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